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| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ul | $303.00 | Add to Cart |
The FOS gene and protein were originally identified as the transforming element in a viral oncogene. The transforming protein was named v-FOS, for viral FOS, and the normal cellular non-transforming proto-oncogene was called c-FOS, for cellular FOS The c-FOS protein is a normal gene acting as an on/off switch controlling the expression of many other genes. Since c-FOS expression is induced in neurons which are rapidly firing action potentials, appropriate c-Fos antibodies can be used to identify activated neurons in tissues. RA22146 was made against recombinant full length human c-FOS expressed in and purified from E. coli. It can be used to identify activated cells in cell culture and in sections and to follow c-FOS expression in western blots of cell and tissue homogenates. Product Highlights: |
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Immunofluorescent analysis of HeLa cells stained with rabbit pAb to c-FOS, RA22146, dilution 1:2,000 in red, and mouse mAb to tubulin in green. The blue is DAPI staining of nuclear DNA.
Immunofluorescent analysis of HeLa cells stained with rabbit pAb to c-FOS, RA22146, dilution 1:2,000 in red, and mouse mAb to tubulin in green. The blue is DAPI staining of nuclear DNA.