ChAT (Choline Acetyltransferase) Antibody

Product Details

Catalog Number: MO20019

Applications: IHC

Type: Mouse IgG

Dilutions: ICC 1:100-1:200; IHC 1:100-1:200; WB 1:250-1:500

Immunogen: Prokaryotic recombinant protein corresponding to the C-terminal region of the human ChAT molecule.

Storage: Store at 4°C short term. Store at -20°C long term. Avoid freeze-thaw cycles.

Shipping: Frozen (Polar Packs)

Format A: Supernatant

Format B: liquid

Species Reactivity: Human

Entrez: 1103

UniProt: P28329

Downloads: Datasheet (pdf)

Downloads: SDS (pdf)

Product Sizes

Size	List Price	Price	Cart
100 ul		$175.00	Add to Cart

Murine choline-O-acetyltransferase (EC 2.3.1.6) is a 71,721 dalton protein(640 amino acids) expressed in cholinergic neurons of both the PNS and CNS. In the CNS, ChAT is expressed in motor neurons and pre-ganglionic autonomic neurons of the spinal cord, a subset of neurons in the neostriatum, and in the basal forebrain. In the PNS, ChAT is expressed in a small subpopulation of sympathetic neurons and in all parasympathetic neurons. ChAT is the enzyme responsible for synthesis of acetylcholine from acetyl-coenzyme A and choline.

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Images

ChAT staining of Human brain, basal ganglia. Note cytoplasmic staining of neurons of the nucleus basalis of Meynert. Paraffin section

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