Product Details
Catalog Number: MO20019
Applications: IHC
Type: Mouse IgG
Dilutions: ICC 1:100-1:200; IHC 1:100-1:200; WB 1:250-1:500
Immunogen: Prokaryotic recombinant protein corresponding to the C-terminal region of the human ChAT molecule.
Storage: Store at 4°C short term. Store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Supernatant
Format B: liquid
Species Reactivity: Human
Entrez: 1103
UniProt: P28329
Downloads: Datasheet (pdf)
Downloads: SDS (pdf)
Product Sizes
| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ul | $175.00 | Add to Cart |
Murine choline-O-acetyltransferase (EC 2.3.1.6) is a 71,721 dalton protein(640 amino acids) expressed in cholinergic neurons of both the PNS and CNS. In the CNS, ChAT is expressed in motor neurons and pre-ganglionic autonomic neurons of the spinal cord, a subset of neurons in the neostriatum, and in the basal forebrain. In the PNS, ChAT is expressed in a small subpopulation of sympathetic neurons and in all parasympathetic neurons. ChAT is the enzyme responsible for synthesis of acetylcholine from acetyl-coenzyme A and choline. |
Images
ChAT staining of Human brain, basal ganglia. Note cytoplasmic staining of neurons of the nucleus basalis of Meynert. Paraffin section