Product Details
Catalog Number: MO20024
Applications: IHC
Type: Mouse IgG
Immunogen: Prokaryotic recombinant protein corresponding to the entire human calretinin molecule. Clone: CAL6
Storage: Store at 4°C short term. Store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Ascites Fluid
Format B: liquid
Species Reactivity: Human
Entrez: 794
UniProt: P22676
Downloads: Datasheet (pdf)
Downloads: SDS (pdf)
Product Sizes
SizeList PricePriceCart
100 ul$155.00Add to Cart

Calretinin  (CAL6). a member of the family of so-called EF-hand proteins that also includes S-100 proteins, is a 29 kDa calcium binding protein that is expressed in central and peripheral nervous system and in many normal and pathological tissues.

Outside the nervous system, calretinin is reported to be expressed in a range of cell types including mesothelial cells, steroid producing cell, (eg adrenal cortical cells, Leydig cells, ovarian theca interna cells as well as Sertoli cells, some neuroendocrine cells, eccrine sweat glands) and other cell types.

The presence of calretinin is reported to be a useful marker primarily for differentiating malignant mesothelioma from carcinomas. Other reports indicate the detection of calretinin is helpful for the differential characterization of ovarian stroma tumors. Calretinin-positive cells have also been reported in the convoluted tubules of the kidney with some antibodies.

Images
Calretinin staining of human mesotheliom. Note cytoplasmic staining of malignant cells. Paraffin section.

Calretinin staining of human mesotheliom. Note cytoplasmic staining of malignant cells. Paraffin section.

Calretinin staining of human mesotheliom. Note cytoplasmic staining of malignant cells. Paraffin section.

Calretinin staining of human mesotheliom. Note cytoplasmic staining of malignant cells. Paraffin section.

Questions?
We can help.

We are building our company one satisfied customer at a time. If you have any questions or concerns, please contact us.

Neuromics
5325 West 74th St., Suite 8
Edina, MN 55439

Toll free: 866-350-1500
Int’l phone: 952-374-6161
Fax: 612-677-3976