Neuromics is excited to announce the release of two more immortalized cancer-associated fibroblast (CAF) types. Our primary CAFs are some of our top-selling cell types, so we continue introducing immortalized versions to complement the primary cells.
- Immortalized Human Ovarian CAFs (cat. CAF112-IM)
- Immortalized Human Lung Squamous Cell Carcinoma CAFs (cat. CA117S-IM)
We immortalize our primary CAFs by injecting hTert-lentiviral particles under specially formulated media. A Puromycin-resistant gene is expressed under the RSV promoter, which allows us to select the transduced cells. While normal CAFs can be passaged 3-5 times, immortalized CAFs can be passaged >10 times.
Image: Immortalized Lung Adenocarcinoma CAFs in culture. Grown using CAF Growth Media (cat. CAFM03)
We encourage you to check out all of our immortalized CAF offerings below. Furthermore, you can check out all human primary cells, iPSC derived cells & cell lines options here.
| Name | Catalog # | Type | Species | Applications | Size | Price |
|---|---|---|---|---|---|---|
| Immortalized Human Colorectal Tumor CAFs | CAF115-IM | Human Primary CAFs | Human | Cell Assays | 1,000,000 cells | $6,628.98 |
| Immortalized Human Kidney CAFs | CAF110-IM | Human Primary CAFs | Human | Cell Assays | 1,000,000 cells | $9,006.60 |
| Immortalized Human Lung Adenocarcinoma CAFs | CAF117-IM | Human Primary CAFs | Human | Cell Assays | 1,000,000 cells | $6,628.98 |
| Immortalized Human Lung Squamous Cell Carcinoma CAFs | CAF117S-IM | Human Primary CAFs | Human | Cell Assays | 1,000,000 Cells | $9,006.60 |
| Immortalized Human Ovarian CAFs | CAF112-IM | Human Primary CAFs | Human | Cell Assays | 1,000,000 Cells | $9,006.60 |
| Immortalized Human Pancreatic CAFs | CAF118-IM | Human Primary CAFs | Human | Cell Assays | 1,000,000 cells | $8,119.20 |