Human Fibroblasts, Cancer-Associated Fibroblasts (CAFs), and Cancer Cells

Neuromics has an extensive offering of Human Fibroblast, Cancer-Associated Fibroblasts (CAFS) and Cancer Cells. These cells are derived from the gastro-intestinal (GI cells), lungs (bronchial cells), ovaries (ovarian cells), pancreas (pancreatic cells), prostate and more. Cancer cells also include prostate and glioblastoma cells.

These cells have been used to study wound healing, cancer (metastasis), cellular senescence, fibrosis, regeneration, drug screening and toxicology, genetics, and the extracellular matrix.

They are widely used and published with increasing frequency. The cells have been used for 3-D modeling, and in single and multi-cell assays. Researchers describe them as potent, pure and easy to culture.

All cells are prepared and manufactured in an ISO 9001:2015 certified environment and ISO 5 cleanroom.

Product Highlights:

Image:Treatment of 2D coculture of A549 (red) cells with primary lung CAFs (Green) with 10 μM of FT234 show that the HDAC11 inhibitor selectively reduces the growth of A549 cells as compared to the Control co-cultures in 48 h. Such an effect was not observed in the negative control FT650 treatment. https://doi.org/10.1038/s41598-020-61295-6.

Cancer Associated Fibroblasts (CAFs)

CAFs are closely associated with primary tumor cells and participate in the neoplastic process. There is reciprocal communication between CAFs and tumor cells through paracrine effects of secreted growth factors, cytokines & chemokines from both fibroblasts, tumor cells and other tumor-associated cells. CAFs are potential target for cancer therapy and enhanced understanding of tumor growth, angiogenesis and metastasis.

Neuromics has access to provide many other types of CAFs. If you have a need beyond what is listed, contact david@neuromics.com with any questions.

Name	Catalog #	Type	Species	Applications	Size	Price
Human Breast CAFs	CAF116	Human Primary CAFs	Human	Cell Assays	1,000,000 cells	$2,792.88
Human Bronchial CAFs	CAF111	Human Primary CAFs	Human	Cell Assays	1,000,000 Cells	$3,078.00
Human Colorectal Tumor CAFs	CAF115	Human Primary CAFs	Human	Cell Assays	1,000,000 cells	$1,294.92
Human Kidney CAFs	CAF110	Human Primary CAFs	Human	Cell Assays	1,000,000 Cells	$3,078.00
Human Liver CAFs	CAF113	Human Primary CAFs	Human	Cell Assays	1,000,000 Cells	$3,078.00
Human Lung Adenocarcinoma CAFs	CAF117	Human Primary CAFs	Human	Cell Assays	1,000,000 cells	$1,294.92
Human Lung Squamous Cell Carcinoma CAFs	CAF117S	Human Primary CAFs	Human	Cell Assays	1,000,000 Cells	$3,078.00
Human Metastatic Ovarian CAFs	CAF114	Human Primary CAFs	Human	Cell Assays	1,000,000 Cells	$3,078.00
Human Ovarian CAFs	CAF112	Human Primary CAFs	Human	Cell Assays	1,000,000 Cells	$3,078.00
Human Pancreatic CAF-Stellate Cells	CAF118	Human Primary CAFs	Human	Cell Assays	1,000,000 Cells	$2,656.80
Human Prostate CAFs	CAF119	Human Primary CAFs	Human	Cell Assays	1,000,000 Cells	$3,078.00

Immortalized Cancer Associated Fibroblasts (CAFs)

These cells are the immortalized versions of our normal cancer associated fibroblasts (CAFs). The cells are immortalized with hTert-lentiviral particles under specially formulated media. Normal CAFs can be passaged 3-5 times, while immortalized CAFs can be passaged >10 times.

Neuromics can immortalized any of our CAF types. Please contact david@neuromics.com for more information.

Name	Catalog #	Type	Species	Applications	Size	Price
Immortalized Human Colorectal Tumor CAFs	CAF115-IM	Human Primary CAFs	Human	Cell Assays	1,000,000 cells	$7,018.92
Immortalized Human Kidney CAFs	CAF110-IM	Human Primary CAFs	Human	Cell Assays	1,000,000 cells	$9,536.40
Immortalized Human Lung Adenocarcinoma CAFs	CAF117-IM	Human Primary CAFs	Human	Cell Assays	1,000,000 cells	$7,018.92
Immortalized Human Lung Squamous Cell Carcinoma CAFs	CAF117S-IM	Human Primary CAFs	Human	Cell Assays	1,000,000 Cells	$9,536.40
Immortalized Human Ovarian CAFs	CAF112-IM	Human Primary CAFs	Human	Cell Assays	1,000,000 Cells	$9,536.40
Immortalized Human Pancreatic CAFs	CAF118-IM	Human Primary CAFs	Human	Cell Assays	1,000,000 cells	$8,596.80

Human Fibroblasts

These human fibroblast cells are suitable for use in derivation of iPS cells and other applications requiring human fibroblasts including vaccine production and studies of cancer-associated fibroblasts (CAFs).

Name	Catalog #	Type	Species	Applications	Size	Price
Cas9-Human Colon Fibroblast Cells	HCF001-CAS	Primary Cells	Human	Cell Assays	500,000 Cells	$5,385.00
Cas9-Human Lung Fibroblast Cells	HLF001-CAS	Primary Cells	Human	Cell Assays	500,000 Cells	$5,385.00
Cas9-Human Pancreatic Fibroblast Cells	HPF001-CAS	Primary Cells	Human	Cell Assays	500,000 Cells	$5,385.00
HEL 299 Cells	HEL001	Primary Cells	Human	Cell Assays	500,000 Cells	$959.04
Human Colon Fibroblast Cells	HCF001	Primary Cells	Human	Cell Assays	500,000 cells	$1,165.32
Human Dermal Fibroblast Cells	HDF001	Primary Cells	Human	Cell Assays	500,000 Cells	$1,165.32
Human Fibroblasts-GFP Expressing	GFP07	Primary Cells	Human	Cell Assays	500,000 Cells	$1,294.92
Human Lung Fibroblast Cells	HLF001	Primary Cells	Human	Cell Assays	500,000 Cells	$1,165.32
Human Pancreatic Fibroblast Cells	HPF001	Primary Cells	Human	Cell Assays	500,000 Cells	$1,165.32
Human Uterine Fibroblast Cells	HUF001	Primary Cells	Human	Cell Assays	500,000 Cells	$1,165.32
Insulin Secreting Human Fibroblast Pancreatic Islet Cells	HPF002	Primary Cells	Human	Cell Assays	500,00 Cells	$2,694.60
MRC-5 Cells	MRC001	Primary Cells	Human	Cell Assays	500,000 Cells	$959.04
WI-38 Cells	WI001	Primary Cells	Human	Cell Assays	500,000 Cells	$959.04

GFP & RFP Expressing Cancer Cells

These human cells are derived from various carcinoma cell lines, with the unique feature of being GFP and RFP expressing. Our selection of cells consists of gastric carcinoma, glioblastoma, prostate carcinoma, and renal adenocarcinoma cells.

Name	Catalog #	Type	Species	Applications	Size	Price
GFP Expressing Human Brain Glioblastoma Cells (LN-18)	TR05-GFP	Primary Cells	Human	Cell Assays	500,000 Cells	$1,224.72
GFP Expressing Human Brain Glioblastoma Cells (LN-229)	TR06-GFP	Primary Cells	Human	Cell Assays	500,000 Cells	$1,224.72
GFP Expressing Human Gastric Carcinoma N87 Cells	TR02-GFP	Primary Cells	Human	Cell Assays	500,000 Cells	$1,294.92
GFP Expressing Human Glioblastoma Cells	TR01-GFP	Primary Cells	Human	Cell Assays	500,000 Cells	$1,294.92
GFP Expressing Human Prostate Carcinoma Cells (DU 145)	TR03-GFP	Primary Cells	Human	Cell Assays	500,000 Cells	$1,294.92
GFP Expressing Human Renal Adenocarcinoma Cells (ACHN)	TR04-GFP	Primary Cells	Human	Cell Assays	500,000 Cells	$1,294.92
RFP Expressing Human Brain Glioblastoma Cells (LN-18)	TR05-RFP	Primary Cells	Human	Cell Assays	500,000 Cells	$1,224.72
RFP Expressing Human Brain Glioblastoma Cells (LN-229)	TR06-RFP	Primary Cells	Human	Cell Assays	500,000 Cells	$1,224.72
RFP Expressing Human Gastric Carcinoma N87 Cells	TR02-RFP	Primary Cells	Human	Cell Assays	500,000 Cells	$1,294.92
RFP Expressing Human Glioblastoma Cells	TR01-RFP	Primary Cells	Human	Cell Assays	500,000 Cells	$1,294.92
RFP Expressing Human Prostate Carcinoma Cells (DU 145)	TR03-RFP	Primary Cells	Human	Cell Assays	500,000 Cells	$1,294.92
RFP Expressing Human Renal Adenocarcinoma Cells (ACHN)	TR04-RFP	Primary Cells	Human	Cell Assays	500,000 Cells	$1,294.92

Human Brain Cancer Cells

These human brain cancer cell lines are ideal for cancer researchers.

Name	Catalog #	Type	Species	Applications	Size	Price
LN-319 Cells	LN001	Primary Cells	Human	Cell Assays	500,000 Cells	$1,069.20
SF-295 Cells	SF001	Primary Cells	Human	Cell Assays	500,000 Cells	$563.76

Human Prostate Cancer Cells

These human prostate cancer cell lines are great for cancer investigators.

Name	Catalog #	Type	Species	Applications	Size	Price
GFP Expressing Human Prostate Carcinoma Cells (DU 145)	TR03-GFP	Primary Cells	Human	Cell Assays	500,000 Cells	$1,294.92
Human Prostate Carcinoma Cells (DU 145)	DU001	Primary Cells	Human	Cell Assays	500,000 Cells	$641.52
Human Prostate Carcinoma Cells (LNCaP)	LNC001	Primary Cells	Human	Cell Assays	500,000 Cells	$699.84
Human Prostate Carcinoma Cells (PC-3)	PC001	Primary Cells	Human	Cell Assays	500,000 Cells	$699.84
Human Prostate Carcinoma Cells (VcaP)	VC001	Primary Cells	Human	Cell Assays	500,000 Cells	$699.84
RFP Expressing Human Prostate Carcinoma Cells (DU 145)	TR03-RFP	Primary Cells	Human	Cell Assays	500,000 Cells	$1,294.92

Media for Fibroblast, CAFs, and Tumor Cells

Media for Fibroblasts, CAFs, and Tumor Cells

Name	Catalog #	Type	Species	Applications	Size	Price
1 X Trypsin-0.53mM EDTA Solution	CCM006			Cell Assays	100 ml	$43.20
AlphaBioCoat Precoated 100 mm Dishes	AC001-100MM	Cell Growth Media	Human	Cell Assays	Pack of 10	$402.00
AlphaBioCoat Precoated 12-Well Plates	AC001-12	Cell Growth Media	Human	Cell Assays	Pack of 10	$352.80
AlphaBioCoat Precoated 150 mm Dishes	AC001-150MM	Cell Growth Media	Human	Cell Assays	Pack of 10	$445.20
AlphaBioCoat Precoated 24-Well Plates	AC001-24	Cell Growth Media	Human	Cell Assays	Pack of 10	$390.00
AlphaBioCoat Precoated 35 mm Dishes	AC001-35MM	Cell Growth Media	Human	Cell Assays	Pack of 10	$205.20
AlphaBioCoat Precoated 48-Well Plates	AC001-48	Cell Growth Media	Human	Cell Assays	Pack of 10	$562.80
AlphaBioCoat Precoated 6-Well Plates	AC001-6	Cell Growth Media	Human	Cell Assays	Pack of 10	$333.60
AlphaBioCoat Precoated 60 mm Dishes	AC001-60MM	Cell Growth Media	Human	Cell Assays	Pack of 10	$279.60
AlphaBioCoat Precoated 96-Well Plates	AC001-96	Cell Growth Media	Human	Cell Assays	Pack of 10	$538.80
AlphaBioCoat Precoated T-175 Flasks	AC001-T175	Cell Growth Media	Human	Cell Assays	Pack of 10	$688.80
AlphaBioCoat Precoated T-25 Flasks	AC001-T25	Cell Growth Media	Human	Cell Assays	Pack of 10	$286.60
AlphaBioCoat Precoated T-75 Flasks	AC001-T75	Cell Growth Media	Human	Cell Assays	Pack of 10	$682.80
AlphaBioCoat Solution	AC001	Cell Growth Media	Human	Cell Assays	20 ml	$243.60
CAF Growth Media	CAFM03	Cell Growth Media	Human	Cell Assays	500 ml	$462.00
Cas9 Fibroblast Growth Media	CAFM04	Cell Growth Media	Human	Cell Assays	500 ml	$330.00
Cell Detachment Solution	ADF001		Human	Cell Assays	50 ml	$70.80
Human Plasma Fibronectin	FB001	Cell Growth Media	Human	Cell Assays	1 mg	$459.60
LN-319 Basal Medium	CCM002	Cell Growth Media	Human	Cell Assays	500 ml	$115.20
LN-319 Growth Medium	CCM001	Cell Growth Media	Human	Cell Assays	500 ml	$158.40
Lung Fibroblast Cell Medium	CCM005	Cell Growth Media	Human	Cell Assays	500 ml	$360.00
Neutralization Solution	NS001	Cell Growth Media	Human	Cell Assays	50 ml	$144.00
SF-295 Basal Medium	CCM004	Cell Growth Media	Human	Cell Assays	500 ml	$115.20
SF-295 Growth Medium	CCM003	Cell Growth Media	Human	Cell Assays	500 ml	$158.40
Stem Cell Complete Low Serum Media	CAFM01	Cell Growth Media	Human	Cell Assays	500 ml	$360.00
Stem Cell Complete Media	CAFM02	Cell Growth Media	Human	Cell Assays	500 ml	$403.20
Universal Coating Solution	AC002	Cell Growth Media	Human	Cell Assays	20 ml	$272.40
Universal Detachment Solution	AD002	Cell Growth Media	Human	Cell Assays	100 ml	$108.00
Universal Full Growth Medium	TM001	Cell Growth Media	Human	Cell Assays	500 ml	$315.60
Universal Neutralization Buffer	NB001	Cell Growth Media	Human	Cell Assays	100 ml	$93.60

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Fibroblasts, CAFs, & Cancer Cells