Last month, we highlighted the use of our human brain microvascular pericytes (cat. HMP104) and human brain astrocytres (cat. HMP202) in long COVID research (learn more). It didn't take long for the same cells to pop up in another new publication. This time, it's in blood-brain barrier (BBB) research.
Image: HBMECs stained with Claudin-5.
Researchers from the University of Nottingham used our primary human brain microvascular endothelial cells (cat. HEC02), brain pericytes, and brain astrocytes to build an in vitro blood-brain barrier (BBB) model. They wanted to evaluate the impact of exposure to Substance P (SP) on the BBB, finding that “SP promoted a reversible decline” in their model. The findings have implications in neurological disease research among other areas. You can explore the full publication here.
This study is just the most recent of the many publications exemplifying the durability and reliability of our primary human central nervous system (CNS) cells. You can find all publications using these cells here, including citations for our primary human neurons (cat. HNC001), human schwann cells (cat. HMP303), immortalized human brain microglia (cat. HBMCs001), and 3D BBB Model (cat. 3D45002).
Beyond CNS cells, we have tons of primary cancer associated fibroblasts (CAFs), cancer cell lines, and primary endothelial cells, just to name a few. You can check out all our cell options here. Like our CNS cells, they are well published (see for yourself). We also have specialized media formulated for each cell type along with other culturing tools to keep your cells safe and healthy.