Product Details
Catalog Number: MO47002
Applications: IF
Type: Mouse IgG
Dilutions: Immunohistochemistry: 1:1,000-2,000
Immunogen: Recombinant human p16INK4A C-terminus protein
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 1029
UniProt: P42771
Downloads: Datasheet (pdf)
Product Sizes
| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ul | $255.00 | Add to Cart |
The p16 (p16INK4A) protein is a cyclin-dependent kinase inhibitor that plays an important regulatory role in the cell cycle. By controlling the transition between the G1 and S phases through regulation of retinoblastoma protein, p16 decelerates cellular differentiation and therefore acts as a tumor suppressor, making it the key marker in several human cancers including head and neck cancer, perianal lesions, melanomas, gliomas, lymphomas, and some types of leukemia. p16 is also clinically indicated in carcinomas of the esophagus, pancreas, lung, biliary tract, liver, colon, and urinary bladder |
Images
Immunohistochemistry staining of human colon tissue using MO47002 P16INK4A Antibody.