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| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ul | $660.00 | Add to Cart |
Mammalian target of rapamycin (mTOR) regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, and transcription. It is is activated in response to nutrients, growth factors and cellular energy. Dysregulated mTOR signaling has been implicated in major diseases These include: cancer, metabolic disorders, neurological diseases, and inflammation. For example, findings demonstrate mTOR signaling hyperactivity in Alzheimer's Disease (AD) brains. |
Images
mTOR (red) staining of L6 myotubes. Nuclei are stained with nuclear antigen antibody (green).
mTOR protein kinase assay: mTOR (dilution -1:1000) immunoprecipitates were incubated at 30°C with recombinant 4E-BP1 and 32P-gATP. Autoradiograph shows 32P incorporated into 4E-BP1.