Product Details
Catalog Number: HMP202
Applications: Cell Assays
Type: Primary Cells
Storage: Keep frozen in liquid nitrogen until plating
Shipping: Frozen (Dry Ice/Liquid Nitrogen)
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
| Size | List Price | Price | Cart |
|---|---|---|---|
| 500,000+ cells - Frozen | $1,136.40 | $965.94 | Add to Cart |
Human Brain Microvascular Astrocytes were initiated by elutriation from dissociated normal human brain cortical tissues. HBAs are shipped at passage 1 on dry ice in a vial (or in a proliferation culture - catalog number: HMP202-T25). Astrocyte-Growth medium containing 5% fetal bovine serum and growth supplement is recommended for culture. Cells have an average additional population doubling levels >15 when cultured. Cells are isolated from healthy non-fetal donors. Explore the related products below to find other cells you might need, including glioblastoma cell lines and other glial cells. Cells are prepared and manufactured in an ISO 9001:2015 certified environment and ISO 5 cleanroom. Product Highlights:
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Supporting Products
| Name | Catalog # | Size |
|---|---|---|
| 1X Phosphate Buffer Solution | PBS300 | 100 ml |
| AlphaBioCoat Solution | AC001 | 20 ml |
| Astrocyte Basal Media | PGB004 | 500 ml |
| Astrocyte-Growth Media | PGB003 | 500 ml |
| Cell Detachment Solution | ADF001 | 50 ml |
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- Product Publications
Product Publications
- Jagannatham Bhupana, Angelid Pabon, Ho Hang Leung, Mohamed Rajmohamed, Sang Hoon Kim, Yan Tong, Mi-Hyeon Jang, and Ching-On Wong. (2024). Endolysosomal Processing of Neuron-Derived Signaling Lipids Regulates Autophagy and Lipid Droplet Degradation in Astrocytes. Research Square. doi: 10.21203/rs.3.rs-4622228/v1
- Arshad Hashmat, Jingyuan Ya, Rais Kadir, Mansour Alwjwaj, and Ulvi Bayraktutan. (2024). Hyperglycaemia Perturbs Blood-Brain Barrier Integrity Through Its Effects on Endothelial Cell Characteristics and Function. Tissue Barriers, 2350821. doi: 10.1080/21688370.2024.2350821
- Xin Gao and Ulvi Bayraktutan. (2023). TNF-α Evokes Blood-Brain Barrier Dysfunction through Activation of Rho-Kinase and Neurokinin 1 Receptor. Immunobiology, 228:(5), 152706. doi: 10.1016/j.imbio.2023.152706
- Xin Gao and Ulvi Bayraktutan. (2023). Substance P Reversibly Compromises the Integrity and Function of Blood-Brain Barrier. Peptides, 167: 171048. doi: 10.1016/j.peptides.2023.171048
- Arpan Acharya, Anoop Ambikan, Michellie Thurman, Mohid Reza Malik, Shetty Ravi Dyavar, Akos Vegvari, Ujjwal Neogi, and Siddappa Byrareddy. (2023). Proteomic Landscape of Astrocytes and Pericytes Infected with HIV/SARS-CoV-2 Mono/Co-Infection, Impacting on Neurological Complications. Research Square. doi: 10.21203/rs.3.rs-3031591/v1
- Yvonne Adams, Anne Skovsbo Clausen, Peter Østrup Jensen, Malin Lager, Peter Wilhelmsson, Anna J. Henningson, Per-Eric Lindgren, Daniel Faurholt-Jepsen, Helene Mens, Peter Kraiczy, Kasper Nørskov Kragh, Thomas Bjarnsholt, Andreas Kjaer, Anne-Mette Lebech, and Anja R. Jensen. (2022). 3D Blood-Brain Barrier-Organoids as a Model for Lyme Neuroborreliosis Highlighting Genospecies Dependent Organotropism. iScience. doi: 10.1016/j.isci.2022.105838
- Elizabeth Evans, Vikas Mishra, Crystal Mallow, Elaine Gersz, Leslie Balch, Alan Howell, Christine Reilly, Ernest Smith, Terrence Fisher, and Maurice Zauderer. (2022). Semaphorin 4D is Upregulated in Neurons of Diseased Brains and Triggers Astrocyte Reactivity. Journal of Neuroinflammation, 19:200. doi: 10.1186/s12974-022-02509-8
- Sabine Heitzeneder, Kristopher R. Bosse, Zhongyu Zhu, Doncho Zhelev, Robbie G. Majzner, Molly T. Radosevich, Shaurya Dhingra, Elena Sotillo, Samantha Buongervino, Guillem Pascual-Pasto, Emily Garrigan, Peng Xu, Jing Huang, Benjamin Salzer, Alberto Delaidelli, Swetha Raman, Hong Cui, Benjamin Martinez, and Crystal L. Mackall. (2021). GPC2-CAR T Cells Tuned for Low Antigen Density Mediate Potent Activity Against Neuroblastoma Without Toxicity. Cancer Cell, 40, 1–17. doi: 10.1016/j.ccell.2021.12.005
- Sorel Kurbegovic, Karina Juhl, Kasper Kildegaard Sorensen, Julie Leth, Gro Linno Willemoe, Anders Christensen, Yvonne Adams, Anja Ramstedt Jensen, Christian Von Buchwald, Jane Skjoth-Rasmussen, Michael Ploug, Knud J. Jensen, Andreas Kjaer. (2021). IRDye800CW Labeled uPAR-Targeting Peptide for Fluorescence-Guided Glioblastoma Surgery: Preclinical Studies in Orthotopic Xenografts.Theranostics, 11(15): 7159-7174. doi: 10.7150/thno.49787
- Yvonne Adams, Rebecca W. Olsen, Anja Bengtsson, Nanna Dalgaard, Mykola Zdioruk, Sanghamitra Satpathi, Prativa K. Behera, Praveen K. Sahu, Sean E. Lawler, Klaus Qvortrup, Samuel C. Wassmer, and Anja T.R. Jensen. (2021). Plasmodium Falciparum Erythrocyte Membrane Protein 1 Variants Induce Cell Swelling and Disrupt the Blood–Brain Barrier in Cerebral Malaria. Journal of Experimental Medicine, 218 (3). doi: 10.1084/jem.20201266
- Yang Wu, Yan Li, Liangqing Zheng, Pengcheng Wang, Yan liu, Yongning Wu, ZhiYong Gonga (2019). The neurotoxicity of Nε-(carboxymethyl)lysine in food processing by a study based on animal and organotypic cell culture. Ecotoxicology and Environmental Safety. https://doi.org/10.1016/j.ecoenv.2019.110077
- Ece Bayir, M. Mert Celtikoglu, Aylin Sendemir. (2018). The use of bacterial cellulose as a basement membrane improves the plausibility of the static in vitro blood-brain barrier model. International Journal of Biological Macromolecules. https://doi.org/10.1016/j.ijbiomac.2018.12.257
- Anders Lundin, Louise Delsing, Maryam Clausen, Piero Ricchiuto, José Sanchez, Alan Sabirsh, Mei Ding, Jane Synnergren, Henrik Zetterberg, Gabriella Brolén, Ryan Hicks, Anna Herland, and Anna Falk. (2018). Human iPS-Derived Astroglia from a Stable Neural Precursor State Show Improved Functionality Compared with Conventional Astrocytic Models. Stem Cell Reports. DOI: https://doi.org/10.1016/j.stemcr.2018.01.021
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Images
Human Astrocytes in culture
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Astrocytes stained with S100 beta (cat no. GT15160)