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| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ug | $365.00 | Add to Cart |
AIRE is a transcriptional regulator that is thought to be important in controlling tissue-specific expression of genes in the thymus. The precise function of the protein is not well defined. It contains zinc finger motifs. The AIRE isoform 1 (AIRE) is a splice variant and is localized to both the nucleus and cytoplasm. Defects in this gene cause the autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). |
Images
AIRE 1 staining (dilution: 0.05µg/ml) of HEK293 cell lysates. Untransfected (Lane 3) and transfected with Human AIRE1 (lane 4). Data kindly provided by Prof. Pärt Peterson, University of Tartu, Estonia.
AIRE1 staining (dilution: 2.5µg/ml) of paraffin-embedded Human Thymus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.