Product Details
Catalog Number: GT41016
Applications: IHC, E
Type: Goat IgG
Immunogen: Peptide with sequence C-SVYLSPSSKPVALA, from the C Terminus of the FOXN1 protein according to NP_003584.2.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 8456
UniProt: O15353
Downloads: Datasheet (pdf)
Product Sizes
| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ug | $365.00 | Add to Cart |
FOX1N or Forkhead box N1 is involved in T-cell development. Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. Defects in FOXN1 are the cause of T-cell immunodeficiency congenital alopecia and nail dystrophy. A disorder characterized by the association of congenital alopecia, severe T-cell immunodeficiency, and ridging and pitting of all nails. |
Images
FOX1N (Dilution:20μg/ml) staining of paraffin embedded Human Thymus Medulla. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Protocol on Data-sheet.