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100 ul | $155.00 | Add to Cart |
CD34 is a type I transmembrane glycophosphoprotein expressed by hematopoietic stem/progenitor cells (HSCs). CD34 may also stimulate proportions of adult human HSCs to differentiate into full-fledged neurons. This may open new possibilities for a high-yield production of neurons from bone marrow. In tumors, CD34 is found in alveolar soft part sarcoma, preB-ALL (positive in 75%), AML (40%), AML-M7 (most), dermatofibrosarcoma protuberans, gastrointestinal stromal tumors, giant cell fibroblastoma, granulocytic sarcoma, Kaposi’s sarcoma, liposarcoma, malignant fibrous histiocytoma, malignant peripheral nerve sheath tumors, mengingeal hemangiopericytomas, meningiomas, neurofibromas, schwannomas, and papillary thyroid carcinoma. |
Images
CD34 staining of human tonsil tissue. Note intense staining of neoplastic endothelial cells and absence of staining of stromal cells. Paraffin section