P2X3

Catalog Number: RA10109

1. Hao-Hao Chen, Muhammad Mohsin, Jia-Yi Ge, Yu-Ting Feng, Jing-Ge Wang, Yu-Sen Ou, Zuo-Jie Jiang, Bo-Ya Hu, and Xing-Jun Liu. (2023). Optogenetic Activation of Peripheral Somatosensory Neurons in Transgenic Mice as a Neuropathic Pain Model for Assessing the Therapeutic Efficacy of Analgesics. ACS Pharmacology & Translational Science. doi: 10.1021/acsptsci.3c00254
2. Takuya Yokoyama, Masato Hirakawa, Kei Mochizuki, Takashi Suzuki, Katsumi Nakajima, and Tomoyuki Saino. (2023). Distribution of P2X3 Purinoceptor-Immunoreactive Sensory Nerve Endings in the Carotid Body of Japanese Macaque (Macaca Fuscata). Anatomical Science International. doi: 10.1007/s12565-023-00735-5
3. Masato Hirakawa, Takuya Yokoyama, Yoshio Yamamoto, and Tomoyuki Saino. (2021). Morphology of P2X3-Immunoreactive Basket-Like Afferent Nerve Endings Surrounding Serosal Ganglia and Close Relationship with Vesicular Nucleotide Transporter-Immunoreactive Nerve Fibers in the Rat Gastric Antrum. Journal of Comparative Neurology. doi: 10.1002/cne.25219
4. Momoko Koizumi, Sayaka Asano, Akihiko Furukawa, Yoshinori Hayashi, Suzuro Hitomi, Ikuko Shibuta, Katsuhiko Hayashi, Fusao Kato, Koichi Iwata, and Masamichi Shinoda. (2021). P2X3 Receptor Upregulation in Trigeminal Ganglion Neurons Through TNFα Production in Macrophages Contributes to Trigeminal Neuropathic Pain in Rats. The Journal of Headache and Pain, 22, 31. doi: 10.1186/s10194-021-01244-4
5. Yoshio Yamamoto, Takuya Yokoyama, and Nobuaki Nakamuta. (2021). Morphology of GNAT3‐Immunoreactive Chemosensory Cells in the Nasal Cavity and Pharynx of the Rat. Journal of Anatomy. doi: 10.1111/joa.13424.
6. Yize Li, Xinying Guo, Linlin Sun, Jifang Xiao, Songxue Su, Shibin Du, Zhen Li, Shaogen Wu, Weili Liu, Kai Mo, Shangzhou Xia, Yun‐Juan Chang, Daniel Denis, and Yuan‐Xiang Tao. (2020). N6‐Methyladenosine Demethylase FTO Contributes to Neuropathic Pain by Stabilizing G9a Expression in Primary Sensory Neurons. Advanced Science. doi: 10.1002/advs.201902402
7. Duan-Duan He, Yu Gao, Shan Wang, Zhong Xie, and Xue-Jun Song. (2020). Systematic Administration of B Vitamins Alleviates Diabetic Pain and Inhibits Associated Expression of P2X3 and TRPV1 in Dorsal Root Ganglion Neurons and Proinflammatory Cytokines in Spinal Cord in Rats. Pain Research and Management, 2020:3740162. doi: 10.1155/2020/3740162
8. Yokoyama, T., Yamamoto, Y., Hirakawa, M., Kato, K. and Saino, T. (2019). Vesicular nucleotide transporter‐immunoreactive type I cells associated with P2X3‐immunoreactive nerve endings in the rat carotid body. J Comp Neurol. doi:10.1002/cne.24837
9. Haruka Masuda  Nobuaki Nakamuta  Yoshio Yamamoto. (2018). Morphology of GNAT3‐immunoreactive chemosensory cells in the rat larynx. Journal of Anatomy https://doi.org/10.1111/joa.12914
10. Peng-Fei Liu, Hong-Zhi Fang, Yan Yang, Qing-Qing Zhang, Qiang-Qiang Zhou, Song-Song Chen, Fang Zhou, Li-Cai Zhang. (2017). Activation of P2X3 receptors in the cerebrospinal fluid-contacting nucleus neurons reduces formalin-induced pain behavior via PAG in a rat model. Neuroscience, doi: 10.1016/j.neuroscience.2017.06.036
11. Diana Sofia Marques Nascimento, Catarina Soares Potes, Miguel Luz Soares, António Carlos Ferreira, Marzia Malcangio, José Manuel Castro-Lopes, and Fani Lourença Moreira Neto. (2017). Drug-Induced HSP90 Inhibition Alleviates Pain in Monoarthritic Rats and Alters the Expression of New Putative Pain Players at the DRG. Mol Neurobiol, doi: 10.1007/s12035-017-0628-x
12. Xing J. & Li J. (2016). Bradykinin Contributes to Sympathetic and Pressor Responses Evoked by Activation of Skeletal Muscle Afferents P2X in Heart Failure. Cell Physiol Biochem, 39:2101-2109. doi: 10.1159/000447906
13. Sam M. Hermes, Michael C. Andresen, Sue A. Aicher. (2015). Localization of TRPV1 and P2X3 in unmyelinated and myelinated vagal afferents in the rat. Journal of Chemical Neuroanatomy, doi: 10.1016/j.jchemneu.2015.12.003
14. Jianfei Guo, Xudong Fu, Xia Cui, Minhua Fan. (2014). Contributions of purinergic P2X3 receptors within the midbrain periaqueductal gray to diabetes-induced neuropathic pain. The Journal of Physiological Sciences, doi: 10.1007/s12576-014-0344-5
15. Longchang Fan, Xiaowei Guan, Wei Wang, Jian-Yuan Zhao, Hongkang Zhang, Vinod Tiwari, Paul N Hoffman, Min Li and Yuan-Xiang Tao. (2014). Impaired neuropathic pain and preserved acute pain in rats overexpressing voltage-gated potassium channel subunit Kv1.2 in primary afferent neurons. Molecular Pain, 10:8. doi: 10.1186/1744-8069-10-8
16. Suzy Krimon, Dionéia Araldi, Filipe César do Prado, Cláudia Herrera Tambeli, Maria Cláudia G. Oliveira-Fusaro, Carlos Amílcar Parada. (2013). P2X3 receptors induced inflammatory nociception modulated by TRPA1, 5-HT3 and 5-HT1A receptors. Pharmacology Biochemistry and Behavior, doi: 10.1016/j.pbb.2013.09.017
17. F.C. Pradoa, D. Araldia, A.S. Vieiraa, M.C.G. Oliveira-Fusarob, C.H. Tambelia, C.A. Parada. (2013). Neuronal P2X3 receptor activation is essential to the hyperalgesia induced by prostaglandins and sympathomimetic amines released during inflammation. Neuropharmacology, doi: 10.1016/j.neuropharm.2012.11.011
18. T. Cho, V. V. Chaban. (2012). Interaction Between P2X3 and Oestrogen Receptor (ER)α/ERβ in ATP-Mediated Calcium Signalling In Mice Sensory Neurones. Journal of Neuroendocrinology, Volume 24, Issue 5, pages 789–797. doi: 10.1111/j.1365-2826.2011.02272.x
19. De Felice, Milena, Sanoja, Raul, Wang, Ruizhong, Vera-Portocarrero, Louis, Oyarzo, Janice, King, Tamara, Ossipov, Michael H., Porreca, Frank. (2011). Engagement of descending inhibition from the rostral ventromedial medulla protects against chronic neuropathic pain. PAIN, 152 (12), p.2701-2709. doi: 10.1016/j.pain.2011.06.008
20. B. Huanga, X. Zhaoc, L.-B. Zhengb, L. Zhanga, B. Nia. (2011). Different expression of tissue inhibitor of metalloproteinase family members in rat dorsal root ganglia and their changes after peripheral nerve injury. Neuroscience, Volume 193, Pages 421-428. doi: 10.1016/j.neuroscience.2011.07.031
21. Timothy K. Y. Kaan, Ping K. Yip, Sital Patel, Meirion Davies, Fabien Marchand, Debra A. Cockayne, Philip A. Nunn, Anthony H. Dickenson, Anthony P. D. W. Ford, Yu Zhong, Marzia Malcangio, and Stephen B. McMahon. (2010). Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats. Brain, 133: 2549 - 2564. doi: 10.1093/brain/awq194
22. Nathaniel A. Sowa, Bonnie Taylor-Blake, and Mark J. Zylka. (2010). Ecto-5'-Nucleotidase (CD73) Inhibits Nociception by Hydrolyzing AMP to Adenosine in Nociceptive Circuits. The Journal of Neuroscience, 30(6):2235-2244. doi: 10.1523/JNEUROSCI.5324-09.2010
23. Michael A. Thacker, Anna K. Clark, Thomas Bishop, John Grist, Ping K. Yip, Lawrence D.F. Moon, Stephen W.N. Thompson, Fabien Marchand, Stephen B. McMahon. (2009). CCL2 is a key mediator of microglia activation in neuropathic pain states. European Journal of Pain, 13, 263–272. doi: 10.1016/j.ejpain.2008.04.017
24. Sylvia Sarman; Jorge Mancini; Ingeborg van der Ploeg; J. Oscar Croxatto; Anders Kvanta; Juan E. Gallo. (2008). Involvement of Purinergic P2 Receptors in Experimental Retinal Neovascularization. Current Eye Research, doi: 10.1080/02713680701885470
25. Ruizhong Wang, Tamara King, Michael H Ossipov, Anthony J Rossomando, Todd W Vanderah, Pamela Harvey, Peter Cariani, Eric Frank, Dinah W Y Sah, Frank Porreca. (2008). Persistent restoration of sensory function by immediate or delayed systemic artemin after dorsal root injury.  Nature Communications, doi: 10.1038/nn2069

Catalog Number: GP10108

1. Kuang-Yi Tseng, Hung-Chen Wang, Yi-Hsuan Wang, Miao-Pei Su, Kai-Feng Cheng, Kuang-I Cheng, and Lin-Li Chang. (2023). Peripheral Nerve Denervation in Streptozotocin-Induced Diabetic Rats Is Reduced by Cilostazol. Medicina, 59(3), 553. doi: 10.3390/medicina59030553
2. Ouyang Chen, Qianru He, Qingjian Han, Kenta Furutani, Yun Gu, Maddie Olexa, and Ru-Rong Ji. (2022). Mechanisms and Treatments of Neuropathic Itch in a Mouse Model of Lymphoma. The Journal of Clinical Investigation.
3. Zacnite Garcia. (2020). Investigating the Molecules, Cells, and Circuits for Aversive Taste Signaling. The University of Texas at San Antonio, Doctoral Dissertation.
4. Lou Beaulieu-Laroche, Marine Christin, Annmarie Donoghue, Francina Agosti, Noosha Yousefpour, Hugues Petitjean, Albena Davidova, Craig Stanton, Uzair Khan, Connor Dietz, Elise Faure, Tarheen Fatima, Amanda MacPherson, Stephanie Mouchbahani-Constance, Daniel G. Bisson, Lisbet Haglund, Jean A. Ouellet, Laura S. Stone, Jonathan Samson, Mary-Jo Smith, Kjetil Ask, Alfredo Ribeiro-da-Silva, Rikard Blunck, Kate Poole, Emmanuel Bourinet, and Reza Sharif-Naeini. (2020). TACAN Is an Ion Channel Involved in Sensing Mechanical Pain. Cell. doi: 10.1016/j.cell.2020.01.033
5. Van B. Lu, Juraj Rievaj, Elisabeth A. O’Flaherty, Christopher A. Smith, Ramona Pais, Luke A. Pattison, Gwen Tolhurst, Andrew B. Leiter, David C. Bulmer, Fiona M. Gribble & Frank Reimann (2019). Adenosine triphosphate is co-secreted with glucagon-like peptide-1 to modulate intestinal enterocytes and afferent neurons. Nature Communications volume 10, Article number: 1029
6. Gabriele Stephan, Lumei Huang, Yong Tang, Sandra Vilotti, Elsa Fabbretti, Ye Yu, Wolfgang Nörenberg, Heike Franke, Flóra Göröncsér, Beáta Sperlágh, Anke Dopychai, Ralf Hausmann, Günther Schmalzing, Patrizia Rubini & Peter Illes. The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel. Nature Communications volume 9, Article number: 1354 (2018) doi:10.1038/s41467-018-03728-5
7. Tanja Bele and Elsa Fabbretti. (2016). The scaffold protein CASK controls ATP release in sensory ganglia upon P2X3 receptor activation and is part of an ATP keeper complex. Journal of Neurochemistry, doi: 10.1111/jnc.13680
8. Saman Rahbar, Wen Pan, Michael G. Jonz. (2016). Purinergic and Cholinergic Drugs Mediate Hyperventilation in Zebrafish: Evidence from a Novel Chemical Screen. PLOS One, doi: 10.1371/journal.pone.0154261
9. Erina Ikeda, Tetsuya Goto, Kaori Gunjigake, Kayoko Kuroishi, Masae Ueda, Shinji Kataoka, Takashi Toyono, Mitsushiro Nakatomi, Yuji Seta, Chiaki Kitamura, Tatsuji Nishihara, Tatsuo Kawamoto. (2016). Expression of Vesicular Nucleotide Transporter in Rat Odontoblasts. ACTA HISTOCHEMICA ET CYTOCHEMICA, doi: 10.1267/ahc.15022
10. Paulino Barragán-Iglesias, Hector I. Rocha-González, Jorge Baruch Pineda-Farias, Janet Murbartián, Beatriz Godínez-Chaparro, Peter S. Reinach, Thiago M. Cunha, Fernando Q. Cunha, Vinicio Granados-Soto. (2014). Inhibition of peripheral anion exchanger 3 decreases formalin-induced pain, European Journal of Pharmacology, doi: 10.1016/j.ejphar.2014.05.029
11. Liron S. Durakua, Mehdi Hossaini, Barthold N. Schüttenhelm, b, Joan C. Holstege, Martijn Baas, Tom J.H. Ruigrok, Erik T. Walbeehm. (2013). Re-innervation patterns by peptidergic Substance-P, non-peptidergic P2X3, and myelinated NF-200 nerve fibers in epidermis and dermis of rats with neuropathic pain. Experimental Neurology, Volume 241, Pages 13–24. doi: 10.1016/j.expneurol.2012.11.029
12. Gary Mo, Jennifer C. Peleshok, Chang-Qing Cao, Alfredo Ribeiro-da-Silva and Philippe Séguéla. (2012). Control of P2X3 channel function by metabotropic P2Y2 UTP receptors in primary sensory neurons. Molecular Pharmacology, doi: 10.1124/mol.112.082099
13. Abeer W Saeed, Alfredo Ribeiro-da-Silva. (2012). Non-peptidergic primary afferents are presynaptic to neurokinin-1 receptor immunoreactive lamina I projection neurons in rat spinal cord. Molecular Pain, 8:64. doi: 10.1186/1744-8069-8-64
14. Anna M.W. Taylora, Maria Osikowicza, Alfredo Ribeiro-da-Silva. (2012). Consequences of the ablation of nonpeptidergic afferents in an animal model of trigeminal neuropathic pain. PAIN, Volume 153, Issue 6, Pages 1311–1319. doi: 10.1016/j.pain.2012.03.023
15. Ji Z-G , Ito S , Honjoh T , Ohta H , Ishizuka T , et al. (2012). Light-evoked Somatosensory Perception of Transgenic Rats That Express Channelrhodopsin-2 in Dorsal Root Ganglion Cells. PLoS ONE, 7(3): e32699. doi: 10.1371/journal.pone.0032699
16. Gabriela Castañeda-Corral, Héctor I. Rocha-González, Beatriz Godínez-Chaparro, Juan Miguel Jiménez-Andrade and Vinicio Granados-Soto. (2011). Role of the spinal Na+/H+ exchanger in formalin-induced nociception. Neuroscience Letters, doi: 10.1016/j.neulet.2011.06.048
17. Anna M.W. Taylora and Alfredo Ribeiro-da-Silva. (2011). GDNF levels in the lower lip skin in a rat model of trigeminal neuropathic pain: Implications for nonpeptidergic fiber reinnervation and parasympathetic sprouting. PAIN, Volume 152, Issue 7, Pages 1502-1510. doi: 10.1016/j.pain.2011.02.035
18. Jennifer C. Peleshok, Alfredo Ribeiro-da-Silva. (2011). Delayed reinnervation by nonpeptidergic nociceptive afferents of the glabrous skin of the rat hindpaw in a neuropathic pain model. The Journal of Comparative Neurology, Volume 519, Issue 1, pages 49–63. doi: 10.1002/cne.22500
19. C.K. Park, J.H. Bae, H.Y. Kim, H.J. Jo, Y.H. Kim, S.J. Jung, J.S. Kim, and S.B. Oh. (2010). Substance P Sensitizes P2X3 in Nociceptive Trigeminal Neurons. Journal of Dental Research, 89: 1154 - 1159. doi: 10.1177/0022034510377094
20. James P. Lund,Somayeh Sadeghi,Tuija Athanassiadis, Nadia Caram Salas, François Auclair, Benoît Thivierge, Isabel Arsenault, Pierre Rompré, Karl-Gunnar Westberg, and Arlette Kolta. (2010). Assessment of the Potential Role of Muscle Spindle Mechanoreceptor Afferents in Chronic Muscle Pain in the Rat Masseter Muscle. PLoS One, 5(6): e11131. doi: 10.1371/journal.pone.0011131
21. Marianna D'Arco, Rashid Giniatullin, Vanessa Leone, Paolo Carloni, Nicol Birsa, Asha Nair, Andrea Nistri, and Elsa Fabbretti. (2009). The C-terminal Src Inhibitory Kinase (Csk)-mediated Tyrosine Phosphorylation Is a Novel Molecular Mechanism to Limit P2X3 Receptor Function in Mouse Sensory Neurons J. Biol. Chem., 284: 21393 - 21401. doi: 10.1074/jbc.M109.023051
22. Anna M.W. Taylor, Jennifer C. Peleshok, Alfredo Ribeiro-da-Silva. (2009). Distribution of P2X3-immunoreactive fibers in hairy and glabrous skin of the rat. Comp. Neurol., 514:555-566. doi: 10.1002/cne.22048
23. Ruizhong Wang, Tamara King, Michael H Ossipov, Anthony J Rossomando, Todd W Vanderah, Pamela Harvey, Peter Cariani, Eric Frank, Dinah W Y Sah, Frank Porreca. (2008). Persistent restoration of sensory function by immediate or delayed systemic artemin after dorsal root injury. Nat Neurosci, doi: 10.1038/nn2069
24. Min Liu, Wenlong Huang, Dongsheng Wu and John V. Priestley. (2006). TRPV1, but not P2X3, requires cholesterol for its function and membrane expression in rat nociceptors. European Journal of Neuroscience, Volume 24 Page 1. doi: 10.1111/j.1460-9568.2006.04889.x
25. Carole Torsney, Rebecca L Anderson, Kerry-Anne G Ryce-Paul, and Amy B MacDermott. (2006). Characterization of sensory neuron subpopulations selectively expressing green fluorescent protein in phosphodiesterase 1C BAC transgenic mice Mol Pain, 2: 17.  doi: 10.1186/1744-8069-2-17
26. Averill S, Michael G, Shortland P, Leavesley R, King V, Bradbury E, McMahon S, and Priestley J. (2004). NGF and GDNF ameliorate the increase in ATF3 expression which occurs in dorsal root ganglion cells in response to peripheral nerve injury.  Eur. J. Neurosci., 19(6):1437-1445. doi: 10.1111/j.1460-9568.2004.03241.x
27. Averill S, Davis DR, Shortland PJ, Priestley JV, Hunt SP. (2002). Dynamic Pattern of Reg-2 Expression in Rat Sensory Neurons after Peripheral Nerve Injury. J. Neurosci., 22(17):7493-7501.

Catalog Number: RA14139

1. Bing-Juin Chiang, Su-Han Mao, Shiu-Dong Chung, and Chiang-Ting Chien. (2021). Adipose-Derived Stem Cell-Derived Microvesicles Prevent Progression to Bladder Underactivity Secondary to Long-Termed Bilateral Partial Iliac Arterial Occlusion-Induced Bladder Ischemia. Research Square. doi: 10.21203/rs.3.rs-832404/v1

1. Takuya Yokoyama, Kazuya Settai, Nobuaki Nakamuta, Yoshio Yamamoto (2018). Distribution and morphology of baroreceptors in the rat carotid sinus as revealed by immunohistochemistry for P2X3 purinoceptors. Histochem Cell Biol https://doi.org/10.1007/s00418-018-1734-1
2. Swathi K. Hullugundi,Michel D. Ferrari, Arn M. J. M. van den Maagdenberg, Andrea Nistri. (2013). The Mechanism of Functional Up-Regulation of P2X3 Receptors of Trigeminal Sensory Neurons in a Genetic Mouse Model of Familial Hemiplegic Migraine Type 1 (FHM-1). PLoS ONE, 8(4): e60677. doi: 10.1371/journal.pone.0060677
3. Min Liu, PhD, MD, Yun-fei Xu, PhD, MD, Yuan Feng, PhD, MD, Fengqiang Yang, MD, Jun Luo, MD, Wei Zhai, PhD, MD, Jian-ping Che, MD, Guang-chun Wang, MD, Jun-hua Zheng, PhD. (2013). Epigallocatechin gallate attenuates interstitial cystitis in human bladder urothelium cells by modulating purinergic receptors. Journal of Surgical Research, doi: 10.1016/j.jss.2012.11.041
4. Xu GY, Winston JH, Shenoy M, Zhou S, Chen JD Z, Pasricha PJ. (2009). The endogenous hydrogen sulfide producing enzyme cystathionine-beta synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome. Molecular Pain, 5:44. doi: 10.1186/1744-8069-5-44
5. Elsa Fabbretti, Elena Sokolova, Lara Masten, Marianna D’Arco, Alessandra Fabbro, Andrea Nistri and Rashid Giniatullin. (2004). Identification of negative residues in the P2X3 ATP receptor ectodomain as structural determinants for desensitization and the Ca2+ sensing modulatory sites. JBC Papers in Press, doi: 10.1074/jbc.M409772200
6. Guang-Yin Xu, Mohan Shenoy, John H Winston, Sahil Mittal  and P Jay Pasricha. (2008). P2X receptor-mediated visceral hyperalgesia in a rat model of chronic visceral hypersensitivity. Gut, doi: 10.1136/gut.2007.134221
7. Elsa Fabbretti, Marianna D'Arco, Alessandra Fabbro, Manuela Simonetti, Andrea Nistri, and Rashid Giniatullin. (2006). Delayed Upregulation of ATP P2X3 Receptors of Trigeminal Sensory Neurons by Calcitonin Gene-Related Peptide. The Journal of Neuroscience, 26(23):6163-6171. doi: 10.1523/JNEUROSCI.0647-06.2006
8. Dorn G, Patel S, Wotherspoon G, Hemmings-Mieszczak M, Barclay J, Natt FJ, Martin P, Bevan S, Fox A, Ganju P, Wishart W, Hall J. (2004). siRNA relieves chronic neuropathic pain. Nucleic Acids Res., 32(5):e49. doi: 10.1093/nar/gnh044
9. Honore P, Kage K, Mikusa J, Watt AT, Johnston JF, Wyatt JR, Faltynek CR, Jarvis MF, Lynch K. (2002). Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats. Pain, 99(1-2):11-9.
10. Sun, Y, Chai, T. (2004). Up-Regulation of P2X3 Receptor During Stretch of Bladder Urothelial Cells From Patients With Interstitial Cystitis. Journal of Urology, 171(1):448-452. doi: 10.1097/01.ju.0000099660.46774.3c
11. Hubscher, Charles H.; Petruska, Jeffrey C.; Rau, Kristofer K.; Johnson, Richard D. (2001). Co-expression of P2X receptor subunits on rat nodose neurons that bind the isolectin GS-I-B4. Neuroreport, 12(13):2995-2997.
12. Fabbretti E, Sokolova E, Masten L, D'Arco M, Fabbro A, Nistri A, and Giniatullin R. (2004). Identification of Negative Residues in the P2X3 ATP Receptor Ectodomain as Structural Determinants for Desensitization and the Ca2+-sensing Modulatory Sites.  J. Biol. Chem., Vol. 279, Issue 51, 53109-53115. doi: 10.1074/jbc.M409772200
13. Sokolova E, Skorinkin A, Fabbretti E, Masten L, Nistri A, and Giniatullin R. (2004). Agonist-dependence of recovery from desensitization of P2X3 receptors provides a novel and sensitive approach for their rapid up or downregulation. British J. of Pharmaco., 141, 1048–1058. doi: 10.1038/sj.bjp.0705701
14. Guang-Yin Xu and Li-Yen Mae Huang. (2004). Ca2++/calmodulin-dependent protein kinase II. PNAS, 101(32): 11868–11873. doi: 0.1073pnas.0401490101
15. Fu X, Nurse C, and Cutz E. (2004). Expression of functional purinergic receptors in pulmonary neuroepithelial bodies and their role in hypoxia chemotransmission. Biol. Chem., 385(3-4), p275. doi: 10.1515/BC.2004.022