Product Details
Catalog Number: RA30002
Applications: IHC
Type: Rabbit IgG
Dilutions: IHC 1:1000-1:2000
Immunogen: Synthetic peptide - KLH conjugated 3rd cytoplasmic domain of human 5-HT1F.
Storage: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Rat
Entrez: 3355
UniProt: P30939
Downloads: Datasheet (pdf)
Product Sizes
| Size | List Price | Price | Cart |
|---|---|---|---|
| 50 ug | $435.00 | Add to Cart |
5HT1F, a Serotonin Receptor, is a member of the GPCR family (subfamily: Serotonin). Expression of 5HT1F has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.Selective 5-HT1F agonists may prove therapeutic in the treatment of migraine headache, lacking the side effects associated with the agonists of the 5-HT1B and 5-HT1D receptors. |
Images
5HT-1F staining of paraffin embedded human cortical tissue.