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| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ul | $409.00 | Add to Cart |
TRPM2 is a member of the melastatin-related TRPM subfamily belonging to the transient receptor potential or TRP channel superfamily. TRPM2 can form a Ca2+-permeable cationic channel activated by intracellular ADP-ribose. The physiological functions of TRPM2 remain largely unknown except that activation of TRPM2 channel can initiate yet unidentified signalling cascades that lead to membrane disruption and eventually cell death. |
Images
TRPM2 (red) and GFAP (green) staining of rat hippocampus. Nclei staining is blue. Image courtesy of Dr. Ji-Zhong Bai, The University of Auckland, New Zealand.
Detection of TRPM2. Lane 1: CHO cells untransfected. Lane 2: CHO cell transfected with rat TRPM2 Lane 3: Mouse cortical neurons (cultured). Photo courtesy of Dr. Paco Herson, Oregon Health & Science University.