Product Details
Catalog Number: RA16100
Applications: ICC, WB, IHC
Type: Rabbit IgG
Immunogen: Peptide from c-terminus of rat mGluR5
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat
Entrez: 2915
UniProt: P41594
Downloads: Datasheet (pdf)
Downloads: SDS (pdf)
Product Sizes
| Size | List Price | Price | Cart |
|---|---|---|---|
| 50 ug | $611.00 | Add to Cart |
Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain. |
Images
mGluR5 immunoreactivity in rat globus pallidus. Images courtesy of Dr. Joyce Besheer, UNC.