5HT Serotonins

Catalog Number: RA24288

1. Ramona M. Rodriguiz, Vineet Nadkarni, Christopher R. Means, Vladimir M. Pogorelov, Yi-Ting Chiu, Bryan L. Roth, and William C. Wetsel. (2021). LSD-Stimulated Behaviors in Mice Require β-Arrestin 2 but Not β-Arrestin 1. Scientific Reports, 11:17690. doi: 10.1038/s41598-021-96736-3
2. Lauren F. Borkowski, Catherine L. Smith, Amy N. Keilholz, and Nicole L. Nichols. (2021). Divergent Receptor Utilization is Necessary for Phrenic Long-Term Facilitation Over the Course of Motor Neuron Loss Following CTB-SAP Intrapleural Injections. Journal of Neurophysiology. doi: 10.1152/jn.00236.2021
3. Ramona M. Rodriguiz, Vineet Nadkarni, Christopher R. Means, Vladimir M. Pogorelov, Yi-Ting Chiu, Bryan L. Roth, and William C. Wetsel. (2021). Genetic Deletion of β-Arrestin 2 Modulates LSD Stimulated Behaviors in Mice. doi: 10.21203/rs.3.rs-544199/v1
4. Sukanya Mozumder, Gopa Mahesh, Krishnamoorthi Srinivasan, Jayati Sengupta, and Sujoy Mukherjee. (2020). Expression and Purification of Functionally Active Serotonin 5-HT2A Receptor in Insect Cells Using Low-Titer Viral Stock. Bio-Protocol 10(15): e3704. doi: 10.21769/BioProtoc.3704
5. Lauren F. Borkowski, Taylor A. Craig, Olivia E. Stricklin, Katherine A. Johnson, and Nicole L. Nichols. (2020). 5-HT2A/B Receptor Expression in the Phrenic Motor Nucleus in a Rat Model of ALS (SOD1G93A). Respiratory Physiology & Neurobiology. doi: 10.1016/j.resp.2020.103471
6. Amanda E Price, Dennis J. Sholler, Sonja J. Stutz, Noelle C. Anastasio, and Kathryn A. Cunningham (2019). Endogenous Serotonin 5-HT2A and 5-HT2C Receptors Associate in the Medial Prefrontal Cortex. ACS Chem. Neurosci., DOI: 10.1021/acschemneuro.8b00669
7. Vanja Dakic, Juliana Minardi Nascimento, Rafaela Costa Sartore, Renata de Moraes Maciel, Draulio B. de Araujo, Sidarta Ribeiro, Daniel Martins-de-Souza , Stevens Rehen. (2017). Short term changes in the proteome of human cerebral organoids induced by 5-methoxy-N,N-dimethyltryptamine. bioRxiv, doi: 10.1101/108159
8. David A. Martin, Charles D. Nichols. (2016). Psychedelics Recruit Multiple Cellular Types and Produce Complex Transcriptional Responses Within the Brain. EBioMedicine, doi: 10.1016/j.ebiom.2016.08.049
9. Xavier Viñals, Estefanía Moreno, Laurence Lanfumey, Arnau Cordomí, Antoni Pastor, Rafael de La Torre, Paola Gasperini, Gemma Navarro, Lesley A. Howell, Leonardo Pardo, Carmen Lluís, Enric I. Canela, Peter J. McCormick, Rafael Maldonado, Patricia Robledo. (2015). Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB₁ and Serotonin 5-HT_2A Receptors. PLOS Biology, doi: 10.1371/journal.pbio.1002194
10. Garcia-Cabrerizo, R. & Garcia-Fuster, M.J. (2015). Chronic MDMA induces neurochemical changes in hippocampus of adolescent and young adult rats: Down-regulation of apoptotic markers. NeuroToxicology, doi: 10.1016/j.neuro.2015.06.001
11. Tania Rivera-Baltanasa, Jose Manuel Olivares, Jose Ramon Martinez-Villamarin, Erin Y. Fenton, Lisa E. Kalynchuk, Hector J. Caruncho. (2014). Serotonin 2A receptor clustering in peripheral lymphocytes is altered in major depression and may be a biomarker of therapeutic efficacy. Journal of Affective Disorders. doi: 10.1016/j.jad.2014.03.011
12. Noelle C. Anastasio, Scott R. Gilbertson, Marcy J. Bubar, Anton Agarkov, Sonja J. Stutz, Yowjiun Jeng, Nicole M. Bremer, Thressa D. Smith, Robert G. Fox, Sarah E. Swinford, Patricia K. Seitz, Marc N. Charendoff, John W. Craft, Jr, Fernanda M. Laezza, Cheryl S. Watson, James M. Briggs, and Kathryn A. Cunningham. (2013). Peptide Inhibitors Disrupt the Serotonin 5-HT2C Receptor Interaction with Phosphatase and Tensin Homolog to Allosterically Modulate Cellular Signaling and Behavior. The Journal of Neuroscience, 33(4):1615-1630; doi: 10.1523/JNEUROSCI.2656-12.2013
13. Prem N. Yadav, Wesley K. Kroeze, Martilias S. Farrell and Bryan L. Roth. (2011). ANTAGONIST FUNCTIONAL SELECTIVITY: 5-HT2A SEROTONIN RECEPTOR ANTAGONISTS DIFFERENTIALLY REGULATE 5-HT2A RECEPTOR PROTEIN LEVEL IN VIVO. JPET, doi: 10.1124/jpet.111.18378
14. Prem N Yadav, Atheir I Abbas, Martilias S Farrell, Vincent Setola, Noah Sciaky, Xi-Ping Huang, Wesley K Kroeze, LaTasha K Crawford, David A Piel, Michael J Keiser, John J Irwin, Brian K Shoichet, Evan S Deneris, Jay Gingrich, Sheryl G Beck and Bryan L Roth. (2010). The Presynaptic Component of the Serotonergic System is Required for Clozapine's Efficacy. Neuropsychopharmacology, doi: 10.1038/npp.2010.195
15. Cullen L. Schmid and Laura M. Bohn. (2010). Serotonin, But Not N-Methyltryptamines, Activates the Serotonin 2A Receptor Via a β-Arrestin2/Src/Akt Signaling Complex In Vivo. J. Neurosci., 30: 13513 - 13524; doi: 10.1523/JNEUROSCI.1665-10.2010
16. Ana C Magalhaes, Kevin D Holmes, Lianne B Dale, Laetitia Comps-Agrar, Dennis Lee, Prem N Yadav, Linsay Drysdale, Michael O Poulter, Bryan L Roth, Jean-Philippe Pin, Hymie Anisman & Stephen S G Ferguson. (2010). CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling. Nature Neuroscience, doi: 10.1038/nn.2529
17. Cullen L. Schmid, Kirsten M. Raehal, and Laura M. Bohn. (2007). Agonist-directed signaling of the serotonin 2A receptor depends on β-arrestin-2 interactions in vivo. PNAS, doi: 10.1073/pnas.0708862105

Catalog Number: RA24288

1. Carmen Marie Deveau. (2021). A New Mechanism of Serotonin Transporter Regulation by Simvastatin and the Isoprenylation Pathway. Indiana University, Doctoral Dissertation

Catalog Number: RA20080

1. Ria S. Peesapati, Brianna L. Austin-Byler, Fathima Zahra Nawaz, Jonathan B. Stevenson, Stanelle A. Mais, Rabia N. Kaya, Michael G. Hassan, Nabraj Khanal, Alexandra C. Wells, Deena Ghiai, Anish K. Garikapati, Jacob Selhub, and Edward T. Kipreos. (2024). A Specific Folate Activates Serotonergic Neurons to Control C. elegans Behavior. Nature Communications, 15(8471). doi: 10.1038/s41467-024-52738-z
2. Katharina Wissmiller, Sara Bilekova, Andras Franko, Stefan Z. Lutz, Miriam Katsburg, Sebastian Gulde, Natalia S. Pellegata, Arnulf Stenzl, Martin Heni, Lucia Berti, Hans-Ulrich Häring, and Heiko Lickert. (2023). Inceptor Correlates with Markers of Prostate Cancer Progression and Modulates Insulin/IGF1 Q1,6 Signaling and Cancer Cell Migration. Molecular Metabolism, 101706. doi: 10.1016/j.molmet.2023.101706
3. Alexandra Aliluev, Sophie Tritschler, Michael Sterr, Lena Oppenländer, Julia Hinterdobler, Tobias Greisle, Martin Irmler, Johannes Beckers, Na Sun, Axel Walch, Kerstin Stemmer, Alida Kindt, Jan Krumsiek, Matthias H. Tschöp, Malte D. Luecken, Fabian J. Theis, Heiko Lickert, and Anika Böttcher. (2021). Diet-Induced Alteration of Intestinal Stem Cell Function Underlies Obesity and Prediabetes in Mice. Nature Metabolism, 3:1202–1216. doi: 10.1038/s42255-021-00458-9

Catalog Number: GT20079

1. Yanyu Zhou, Xiaoqi Lin, Yingfu Jiao, Dan Yang, Zhengyu Li, Ling Zhu, Yixuan Li, Suqing Yin, Quanfu Li, Saihong Xu, Dan Tang, Song Zhang, Weifeng Yu, Po Gao, and Liqun Yang. (2024). A Brain-to-Liver Signal Mediates the Inhibition of Liver Regeneration Under Chronic Stress in Mice. Nature Communications, 15:10361. doi: 10.1038/s41467-024-54827-5
2. Yingfu Jiao, Po Gao, Li Dong, Xiaowei Ding, Youqiang Meng, Jiahong Qian, Ting Gao, Ruoxi Wang, Tao Jiang, Yunchun Zhang, Dexu Kong, Yi Wu, Sihan Chen, Saihong Xu, Dan Tang, Ping Luo, Meimei Wu, Li Meng, Daxiang Wen, Changhao Wu, Guohua Zhang, Xueyin Shi, Weifeng Yu, and Weifang Rong. (2022). Molecular Identification of Bulbospinal ON Neurons by GPER Which Drives Pain And Morphine Tolerance. The Journal of Clinical Investigation.
3. Weifang Rong, Ting Gao, Li Dong, Jiahong Qian, Xiaowei Ding, Yi Zheng, Meimei Wu, Li Meng, Yingfu Jiao, Po Gao, Ping Luo, Guohua Zhang, Changhao Wu, and Xueyin Shi. (2021). G-Protein-Coupled Estrogen Receptor (GPER) in the Rostral Ventromedial Medulla Is Essential for Mobilizing Descending Inhibition of Itch. Journal of Neuroscience, 41(37), 7727-7741. doi: 10.1523/JNEUROSCI.2592-20.2021

1. Sean C. Godar, Laura J. Mosher, Simona Scheggi, Paola Devoto, Kelly M. Moench, Hunter J. Strathman, Cori  M. Jones, Roberto Frau, Miriam Melis, Carla Gambarana, Brent Wilkinson, M. Graziella DeMontis, Stephen C. Fowler, Marcelo P. Coba, Cara L. Wellman, Jean C.Shih, Marco Bortolato. (2019). Gene-environment interactions in antisocial behavior are mediated by early-life 5-HT2A receptor activation. Neuropharmacology. https://doi.org/10.1016/j.neuropharm.2019.01.028
2. Małgorzata Lehner, Ewa Taracha, Anna Skórzewska, Piotr Maciejak, Aleksandra Wisłowska-Stanek, Małgorzata Zienowicz, Janusz Szyndler, Andrzej Bidziński and Adam Płaźnik. (2006). Behavioral, immunocytochemical and biochemical studies in rats differing in their sensitivity to pain. Behavioural Brain Research, doi: 10.1016/j.bbr.2006.03.044