Product Details
This product has been discontinued and is no longer available. Neuropeptide Y is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. Two major subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria. NPY receptors, such as NPY1R, have been identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, and aortic smooth muscle. Product Highlights: |
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- Product Publications
Product Publications
- Danqing Dai, Tiantian Zhao, Zhen Li, Wanrong Li, Aiwen Chen, Yali Tang, Xiao-Fei Gao, and Lize Xiong. (2024). The Plasticity of Neuropeptide Y-Y1 Receptor System on Tac2 Neurons Contributes to Mechanical Hyperknesis During Chronic Itch. Theranostics, 14(1): 363-378. doi: 10.7150/thno.89433
- Chunxiao Yang, Zihua Gong, Xiaochen Zhang, Shuai Miao, Bozhi Li, Wei Xie, Tao Wang, Xun Han, Liang Wang, Zhao Dong, and Shengyuan Yu. (2023). Neuropeptide Y in the Medial Habenula Alleviates Migraine-Like Behaviors through the Y1 Receptor. The Journal of Headache and Pain, 24, 61. doi: 10.1186/s10194-023-01596-z
- Tyler S. Nelson, Weisi Fu, Renée R. Donahue, Gregory F. Corder, Tomas Hökfelt, Ronald G. Wiley & Bradley K. Taylor. (2019). Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn. Scientific Reports volume 9, Article number: 7248. https://doi.org/10.1038/s41598-019-43493-z
- Matthew Klompusa, Winnie Hoa, Keith A. Sharkeya and Derek M. McKaya. (2010). Antisecretory effects of neuropeptide Y in the mouse colon are region-specific and are lost in DSS-induced colitis. Regulatory Peptides, Volume 165, Issues 2-3, Pages 138-145. doi: 10.1016/j.regpep.2010.05.014
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Images
NPY Y1 immunofluorescent of Rat DRG cells visualised by FITC. Dilution 1:500 .
NPY Y1 immunofluorescent of Rat DRG cells visualised by FITC. Dilution 1:500 .