Product Details
Catalog Number: MO20014
Applications: WB, IHC, FC
Type: Mouse IgG
Immunogen: Clone: PC10. Rat PCNA induced in the protein A expression vector pR1T2T (Wassem and Lane, 1990).
Storage: Store at 4°C short term. Store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat, Primate
Entrez: 5111
UniProt: P12004
Downloads: SDS (pdf)
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ul$155.00Add to Cart

Proliferating cell nuclear antigen (PCNA) is a 36kD protein which is highly conserved between species. PCNA functions as a co-factor for DNA polymerase delta in S phase and also during DNA synthesis associated with DNA damage repair mechanisms. The PCNA molecule has a half-life in excess of 20 hours, and therefore, may be detected in non-cycling cells eg those in G0 phase.

Images

PCNA staining of Human seminoma: Note nuclear staining of proliferating tumor cells. Paraffin section.

PCNA staining of Human seminoma: Note nuclear staining of proliferating tumor cells. Paraffin section.

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