Product Details
Transforming growth factor beta (TGFB) inhibits cell proliferation and stimulates cell differentiation. This is achieved through a receptor complex of types I and II TGFB receptors. The type II receptor is a transmembrane serine/threonine kinase which is able to bind TGFB and transactivate the type I receptor. TGFB receptors are found in all myometrial tissues and, in the kidney, they are found exclusively in renal tubular cells. In normal gastric mucosa, type I and II receptors are demonstrated in fundic glands, but not on surface mucous cells and in normal small bowel and colon, TGFB receptors are expressed in the epithelial cells of the upper crypts. |
- Product Reviews
Leave a review for this product and you could be eligible for a $10 Starbucks gift card.
- Product Publications
Product Publications
- Kenichi Harada, Yasunori Sato, Hiroko Ikeda, Kumiko Isse, Satoru Ozaki, Mio Enomae, Kazunori Ohama, Kazuyoshi Katayanagi, Hiroshi Kurumaya, Akira Matsui, Yasuni Nakanuma. (2008). Epithelial-mesenchymal transition induced by biliary innate immunity contributes to the sclerosing cholangiopathy of biliary atresia. The Journal of Pathology, Volume 217 Issue 5, Pages 654 - 664. doi: 10.1002/path.2488
If you've used this product in a publication, let us know. Email pshuster@neuromics.com, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Related Products
Name Catalog # Size Angiopoietin-1 (ANG-1) RA26000 100 ul Artemin RA19009 100 ul BDNF GT41014 100 ug CREB MO18006 100 ul CYR61 RA25061 100 ul FGF-2 MO27001 500 ug GATA3 MO47046 100 ug GDNF Receptor Alpha 3 RA30017 50 ug Her2/Neu MO47003 100 ul IGF1R (Insulin-Like Growth Factor Receptor 1) RA21017 50 ug KDR (Kinase Insert Domain Receptor) RA21018 50 ug Notch3 RA19070 100 ug PCNA MO20014 100 ul phospho-Kidins220 (ARMS) RA19020 100 ul phospho-TrkA(Tyr490) RA18018 100 ul pre-pro Enkephalin RA14142 50 ul PTGDS RA25023 100 ul RHEB RA30052 50 ug SMAD-2 RA21025 50 ug SMAD3 RA30033 50 ug TGF beta MO20012 100 ul. TNFRSF1 (Tumor Necrosis Factor Receptor Superfamily, Member 1A), N terminal region RA21029 50 ug Transforming Growth Factor (TGF) beta 1, middle region RA21028 50 ug VEGF R2 (FLK1/KDR) RA25011 500 ul VEGF R2 (FLK1/KDR) RA25011 100 ul VEGF R3 (Flt-4) MO20013 100 ul Wnt10a RA30027 50 ug Wnt2b RA30030 50 ug Wnt8a RA30029 50 ug
Images
TGF Beta R (Type1) staining of paraffin embedded Human colon, ulcerative colitis. Note membrane staining of a proportion of epithelial cells and lymphocytes.
TGF Beta R (Type1) staining of paraffin embedded Human colon, ulcerative colitis. Note membrane staining of a proportion of epithelial cells and lymphocytes.