Product Details
Catalog Number: CH23021
Applications: WB, IHC
Type: Chicken IgY
Immunogen: Synthetic peptide-.Keyhole Limpet Hemocyanin (KLH)-conjugate of a synthetic peptide corresponding to a region near the center of the extracellular domain of the CD11b protein.
Storage: Store at 4°C in the dark
Shipping: Ambient
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Entrez: 3684
UniProt: P11215
RRID: AB_2737146
Downloads: Datasheet (pdf)
This product is no longer available - Contact david@neuromics.com with any questions CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is also a marker for hematopoietic/neural stem and progenitor cells and microglia. Mutations in the CD11b protein have been assosicated with the autoimmune disease lupus, and CD11b antibodies are therefore commonly in immunology studies. |
Images
CD11b or OX-42 staining of adult mouse cerebral cortex sections showing microglial cells and their processes. Courtesy of Dr. Felix Eckenstein (University of Vermont).