Product Details
This product is no longer available - Contact david@neuromics.com with any questions Human TH (EC 1.14.16.2) is a 58,523 dalton protein (528 amino acids) responsible for the enzymatic conversion of l-tyrosine to l-DOPA (dihydroxyphenylalanine). This enzyme is expressed in all catecholaminergic neurons of the CNS and PNS. In the CNS, TH-positive neurons can be found within the substantia nigra, ventral tegmental area, locus ceruleus, and hypothalamus. In the PNS, TH-positive neurons can be found within the sympathetic chain, pre-vertebral ganglia and the adrenal medulla. |
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- Product Publications
Product Publications
- Manuel J. Ferreira-Pinto, Harsh Kanodia, Antonio Falasconi, Markus Sigrist, Maria S. Esposito, and Silvia Arber. (2021). Functional Diversity for Body Actions in the Mesencephalic Locomotor Region. Cell. doi: 10.1016/j.cell.2021.07.002
- Yu-Wei Chen, Manasmita Das, Esteban A. Oyarzabal, Qing Cheng, Nicholas W. Plummer, Kathleen G. Smith, Grace K. Jones, Daniel Malawsky, Jerrel L. Yakel, Yen-Yu Ian Shih & Patricia Jensen (2018). Genetic identification of a population of noradrenergic neurons implicated in attenuation of stress-related responses. Molecular Psychiatry. DOI https://doi.org/10.1038/s41380-018-0245-8
- Hans-Ulrich Fried, U. Benjamin Kaupp and Frank Müller. (2010). Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice. Cell Tissue Res., 339(3): 463–479. doi: 10.1007/s00441-009-0904-9
- Sujoy K. Dhara, Brian A. Gerwe, Anirban Majumder, Mahesh C. Dodla, Nolan L. Boyd, David W. Machacek, Kowser Hasneen, Steven L. Stice. (2009). Genetic Manipulation of Neural Progenitors Derived from Human Embryonic Stem Cells. Tissue Engineering Part A. doi: 10.1089/ten.tea.2009.0155
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Images
TH (tyrosine hydroxylase, an excitatory neuronal marker) staining of STEMEZ(TM) hNP1 Human Neural Progenitors. doi:10.1089/ten.tea.2009.0155.
TH (tyrosine hydroxylase, an excitatory neuronal marker) staining of STEMEZ(TM) hNP1 Human Neural Progenitors. doi:10.1089/ten.tea.2009.0155.
Tissue section through an adult mouse brain showing TH (red staining) in catecholaminergic neurons of the substantia nigra (pars compacta). The green staining is the autofluorescence of green fluorescent protein (GFP) in neurons in this transgenic animal.
Tissue section through an adult mouse brain showing TH (red staining) in catecholaminergic neurons of the substantia nigra (pars compacta). The green staining is the autofluorescence of green fluorescent protein (GFP) in neurons in this transgenic animal.