Product Details
Catalog Number: CH23001
Applications: ICC, WB, IHC
Type: Chicken IgY
Dilutions: ICC 1:100-1:200; IHC 1:100-1:200; WB 1:250-1:500
Immunogen: Peptide common to mouse (NP_057910) Nestin
Storage: Store at 4°C in the dark
Shipping: Ambient
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat
Entrez: 10763
UniProt: P48681
RRID: AB_2148920
Downloads: Datasheet (pdf)
This product is no longer available - Contact david@neuromics.com with any questions Nestin is expressed in neural crest cells, CNS neural stems cells, as well as a few non-neural cell types in the embryo, including cells within the pancreatic islets of Langerhans and the limb bud. Nestin is an intermediate filament-associated protein, and contributes to the cytoskeleton. |
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- Product Publications
Product Publications
- Valeria Bortolotto, Pier Luigi Canonico, and Mariagrazia Grilli. (2021). β2 and α2 Adrenergic Receptors Mediate the Proneurogenic in vitro Effects of Norquetiapine. Neural Regeneration Research, 16(10), 2041-2047. doi: 10.4103/1673-5374.308097
- Jes Alexander, Quincey C. LaPlant, Siobhan S. Pattwell, Frank Szulzewsky, Patrick J. Cimino, Francesca P. Caruso, Pietro Pugliese, Zhihong Chen, Florence Chardon, Andrew J. Hill, Cailyn Spurrell, Dakota Ahrendsen, Alexander Pietras, Lea M. Starita, Dolores Hambardzumyan, Antonio Iavarone, Jay Shendure, and Eric C. Holland. (2020). Multimodal Single‐Cell Analysis Reveals Distinct Radioresistant Stem‐Like and Progenitor Cell Populations in Murine Glioma. Glia. doi: 10.1002/glia.23866
- Marco Emilia, Fiorenza Stagni, Maria Elisa Salvalai, Beatrice Uguagliati, Andrea Giacomini, Christelle Albach, Marie-Claude Potier, Mariagrazia Grilli, Renata Bartesaghi, and Sandra Guidi. (2020). Neonatal Therapy with Clenbuterol and Salmeterol Restores Spinogenesis and Dendritic Complexity in the Dentate Gyrus of the Ts65Dn Model of Down Syndrome. Neurobiology of Disease. doi: 10.1016/j.nbd.2020.104874
- Fiorenza Stagni, Maria Elisa Salvalai, Andrea Giacomini, Marco Emili, Beatrice Uguagliati, Er Xia, Mariagrazia Grilli, Renata Bartesaghi, Sandra Guidi (2019). Neonatal treatment with cyclosporine A restores neurogenesis and spinogenesis in the Ts65Dn model of Down syndrome. Neurobiology of Disease. Volume 129, September 2019, Pages 44-55. doi: https://doi.org/10.1016/j.nbd.2019.05.005
- Doris Lam, Heather A. Enright, Jose Cadena, Sandra K. G. Peters, Ana Paula Sales, Joanne J. Osburn, David A. Soscia, Kristen S. Kulp, Elizabeth K. Wheeler & Nicholas O. Fischer (2019). Tissue-specific extracellular matrix accelerates the formation of neural networks and communities in a neuron-glia co-culture on a multi-electrode array. Scientific Reports volume 9, Article number: 4159. https://doi.org/10.1038/s41598-019-40128-1
- R. Joshi, B. Fuller, B. Mosadegh, H. Tavana. (2018). Stem Cell Colony Interspacing Effect on Differentiation to Neural Cells. Journal of Tissue Engineering and Regenerative Medicine. Doi: 10.1002/term.2739
- Ramila Joshi, Pradip Shahi Thakuri, James C. Buchanan, Jun Li, Hossein Tavana. (2017). Microprinted Stem Cell Niches Reveal Compounding Effect of Colony Size on Stromal Cells-Mediated Neural Differentiation. Advanced Healthcare Materials. doi: 10.1002/adhm.2017008
- Fraser I. Young, Marc Keruzore, Xinsheng Nan, Nicole Gennet, Eric J. Bellefroid, and Meng Li. (2017). The doublesex-related Dmrta2 safeguards neural progenitor maintenance involving transcriptional regulation of Hes1. PNAS, doi: 10.1073/pnas.1705186114
- Hayk Harutyunyan, Svetlana Sharoyan, Alvard Antonyan, Sona Mardanyan. (2017). Herb Preparations Improve the Viability of Hippocampal Cells Suppressed by Amyloid Beta (1-42) Peptide. World Journal of Pharmaceutical Sciences, ISSN (Online): 2321-3086
- R Joshi, JC Buchanan, H Tavana. (2017). Self-Regulatory Factors of Embryonic Stem Cells in Co-Culture with Stromal Cells Enhance Neural Differentiation. Integrative Biology. doi: 10.1039/C7IB00038C
- Ramila Joshi, James Carlton Buchanan, Sailaja Paruchuri, Nathan Morris, Hossein Tavana. (2016). Molecular Analysis of Stromal Cells-Induced Neural Differentiation of Mouse Embryonic Stem Cells. PLOS One, doi: 10.1371/journal.pone.0166316
- Suzana Cvijetic, Valeria Bortolotto, Marcello Manfredi, Elia Ranzato, Emilio Marengo, Rita Salem, Pier Luigi Canonico, Mariagrazia Grilli. (2016). Cell autonomous and noncell-autonomous role of NF-κB p50 in astrocyte-mediated fate specification of adult neural progenitor cells. Glia, doi: 10.1002/glia.23085
- Shinya Hirota, Thomas P. Clements, Leung K. Tang, John E. Morales, Hye Shin Lee, S. Paul Ohµ, Gonzalo M. Rivera, Daniel S. Wagner, and Joseph H. McCarty. (2015). Neuropilin-1 Balances Beta8 Integrin-Activated TGFBeta Signaling to Control Sprouting Angiogenesis in the Brain. Development, doi: 10.1242/dev.113746
- Gleave JA, Lerch JP, Henkelman RM, Nieman BJ. (2013). A Method for 3D Immunostaining and Optical Imaging of the Mouse Brain Demonstrated in Neural Progenitor Cells. PLoS ONE, 8(8): e72039. doi: 10.1371/journal.pone.0072039
- Maria Maddalena Valente, Valeria Bortolotto, Bruna Cuccurazzu, Federica Ubezio, Vasco Meneghini, Maria Teresa Francese, Pier Luigi Canonico, Mariagrazia Grilli. (2012). Alpha2delta ligands act as positive modulators of adult hippocampal neurogenesis andprevent depressive-like behavior induced by chronic restraint stress. Molecular Pharmacology, doi: 10.1124/mol.112.077636
- J H Tchaicha, A K Mobley, M G Hossain, K D Aldape and J H McCarty. (2010). A mosaic mouse model of astrocytoma identifies αvβ8 integrin as a negative regulator of tumor angiogenesis. Oncogene, doi: 10.1038/onc.2010.199
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Images
A tissue section through an e13 mouse brain showing Nestin (green staining) in neural stem cells of the ventricular zone of the CNS. DAPI (blue staining) allows visualization of nuclei.
A tissue section through an e13 mouse brain showing Nestin (green staining) in neural stem cells of the ventricular zone of the CNS. DAPI (blue staining) allows visualization of nuclei.