Product Details
Catalog Number: CH23005
Applications: ICC, WB, IHC
Type: Chicken IgY
Dilutions: ICC 1:100-1:200; IHC 1:100-1:200; WB 1:250-1:500
Immunogen: Peptide common to rat (AAM28438) and human (AAL28094) Tuj 1 and Neuron specific class II beta tunulin
Storage: Store at 4°C in the dark
Shipping: Ambient
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Entrez: 10381
UniProt: Q13509
RRID: AB_2210684
Downloads: Datasheet (pdf)
This product is no longer available - Contact david@neuromics.com with any questions Human β-Tubulin 3 is a 50,432 dalton structural protein (450 amino acid) expressed in neurons of the PNS and CNS. It contributes to microtubule stability in neuronal cell bodies and axons, and plays a role in axonal transport. Product Highlights: |
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- Product Publications
Product Publications
- Jonathan Frew and Haakon Berge Nygaard. (2021). Neuropathological and Behavioral Characterization of Aged Grn R493X Progranulin-Deficient Frontotemporal Dementia Knockin Mice. Acta Neuropathologica Communications, 9:57. doi: 10.1186/s40478-021-01158-x
- Man Wang, Yuechen Han, Xue Wang, Shuo Liang, Chuan Bo, Zhenbiao Zhang, Mingming Wang, Lei Xu, Daogong Zhang, Wenwen Liu, and Haibo Wang. (2021). Characterization of EGR-1 Expression in the Auditory Cortex Following Kanamycin-Induced Hearing Loss in Mice. Journal of Molecular Neuroscience. doi: 10.1007/s12031-021-01791-0.
- Kevin Y. Zhang, Caitlyn Tuffy, Joseph L. Mertz, Sarah Quillen, Laurence Wechsler, Harry A. Quigley, Donald J. Zack, and Thomas V. Johnson. (2020). Role of the Internal Limiting Membrane in Structural Engraftment and Topographic Spacing of Transplanted Human Stem Cell-Derived Retinal Ganglion Cells. Stem Cell Reports, 16, 1-19. Doi: 10.1016/j.stemcr.2020.12.001
- Guang Wang, Jia-Qi Lu, Yong Ding, Tonghua Zhang, Jin-Huan Song, Denglu Long, Jianxin Liang, Xin Cheng, Zhenpeng Si, Guolong Qi, Xiaohua Jiang, and Xuesong Yang. (2020). Baicalin Rescues Hyperglycemia-Induced Neural Tube Defects Via Targeting on Retinoic Acid Signaling. American Journal of Translational Research, 12(7): 3311–3328.
- Heather A. Enright, Doris Lam, Aimy Sebastian, Ana Paula Sales, Jose Cadena, Nicholas R. Hum, Joanne J. Osburn, Sandra K. G. Peters, Bryan Petkus, David A. Soscia, Kristen S. Kulp, Gabriela G. Loots, Elizabeth K. Wheeler, and Nicholas O. Fischer. (2020). Functional and Transcriptional Characterization of Complex Neuronal Co-Cultures. Scientific Reports, 10:11007. doi: 10.1038/s41598-020-67691-2
- Jonathan Frew, Alireza Baradaran-Heravi, Aruna D. Balgi, Xiujuan Wu, Tyler D. Yan, Steve Arns, Fahimeh S. Shidmoossavee, Jason Tan, James B. Jaquith, Karen R. Jansen-West, Francis C. Lynn, Fen-Biao Gao, Leonard Petrucelli, Howard H. Feldman, Ian R. Mackenzie, Michel Roberge & Haakon B. Nygaard (2020). Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency. Molecular Neurodegeneration volume 15, Article number: 21. https://doi.org/10.1186/s13024-020-00369-5
- David A. Soscia, Doris Lam, Angela C. Tooker, Heather A. Enright, Michael Triplett, Piyush Karande, Sandra K. G. Peters, Ana Paula Sales, Elizabeth K. Wheeler and Nicholas O. Fischer. (2020). A flexible 3-dimensional microelectrode array for in vitro brain models. Lab Chip. DOI: 10.1039/C9LC01148J
- Doris Lam, Heather A. Enright, Jose Cadena, Sandra K. G. Peters, Ana Paula Sales, Joanne J. Osburn, David A. Soscia, Kristen S. Kulp, Elizabeth K. Wheeler & Nicholas O. Fischer (2019). Tissue-specific extracellular matrix accelerates the formation of neural networks and communities in a neuron-glia co-culture on a multi-electrode array. Scientific Reportsvolume 9, Article number: 4159. https://doi.org/10.1038/s41598-019-40128-1
- Laura F. Corns, Lucy Atkinson, Jill Daniel, Ian J. Edwards, Lauryn New, Jim Deuchars and Susan A. Deuchars. (2015). Cholinergic Enhancement of Cell Proliferation in the Postnatal Neurogenic Niche of the Mammalian Spinal Cord. Stem Cells, doi: 10.1002/stem.2077
- Nuno Jorge Lamas, Bethany Johnson-Kerner, Laurent Roybon, Yoon A. Kim, Alejandro Garcia-Diaz, Hynek Wichterle, Christopher E. Henderson. (2014). Neurotrophic Requirements of Human Motor Neurons Defined Using Amplified and Purified Stem Cell-Derived Cultures. PLOS ONE, doi: 10.1371/journal.pone.0110324
- Shintaro Takahashi, Hironori Yamazoe, Fumihiro Sassa, Hiroaki Suzuki and Junji Fukuda. (2009). Preparation of coculture system with three extracellular matrices using capillary force lithography and layer-by-layer deposition. Journal of Bioscience and Bioengineering, doi: 10.1016/j.jbiosc.2009.06.013
Product Patent Application
- Valentina Fossati and Panagiotis Douvaras. (2020). Functional Oligodendrocytes Derived from Pluripotent Stem Cells and Methods of Making and Using the Same. United States Patent Application 20200399595
- Steven L. Stice, Franklin West, and Yangqing Lu. (2020). Avian Induced Pluripotent Stem Cells and Their Use. United States Patent Application 20200208119
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Images
Dissociated cell culture of a neonatal mouse brain showing β-Tubulin 3 (green staining) of neurons. These cultures were counter-stained with a rabbit anti-GFAP antibody (red staining) to identify astrocytes, and with DAPI (blue staining) to localize nuclei.
Dissociated cell culture of a neonatal mouse brain showing β-Tubulin 3 (green staining) of neurons. These cultures were counter-stained with a rabbit anti-GFAP antibody (red staining) to identify astrocytes, and with DAPI (blue staining) to localize nuclei.