Product Details
Catalog Number: RA30062
Applications: WB, IHC
Type: Rabbit IgG
Immunogen: KLH-conjugated synthetic peptide corresponding to to amino acids at the C-terminus of human CARD8.
Storage: Store at 4°C. Do not freeze.
Shipping: Refrigerated (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 22900
UniProt: Q9Y2G2
Downloads: Datasheet (pdf)
Product Sizes
| Size | List Price | Price | Cart |
|---|---|---|---|
| 50 ug | $435.00 | Add to Cart |
CARD8, a novel CARD-containing protein, was recently identified. This protein interacts with DRAL, a p53-responsive protein implicated in the induction of apoptosis, and caspase-1 and its related proteins ICEBERG and pesudo-ICE. CARD8 potently inhibits NF-kB signaling, which plays a key role in inflammation, and may contribute to avoid a pathologic activation of NF-kB. |
Images
Human Spleen (formalin-fixed, paraffin-embedded) stained with CARD8 antibody at 5.0 ug/ml followed by Goat anti-rabbit IgG, Biotin-Catalog#:GT30001, alkaline phosphatase-streptavidin and chromogen.