Product Details
Catalog Number: RA30054
Applications: WB, IHC
Type: Rabbit IgG
Immunogen: KLH conjugated synthetic peptide- corresponding to 13 amino acids near the center of human TLR6.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 8795
UniProt: O14763
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
50 ug$435.00Add to Cart

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.

TLR2 Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.  It could  also promote apoptosis in response to lipoproteins.

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Images

TLR2 staining of Human Lung, Alveolar Macrophages (formalin-fixed, paraffin-embedded) at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

TLR2 staining of Human Lung, Alveolar Macrophages (formalin-fixed, paraffin-embedded) at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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