Product Details
Catalog Number: RA24427
Applications: IHC, IF
Type: Rabbit IgG
Immunogen: Calbindin D -28K purified from bovine cerebellum
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Whole serum
Format B: lyophilized
Species Reactivity: Mouse, Rat
Entrez: 793
UniProt: P05937
Downloads: Datasheet (pdf)
Product Sizes
| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ul | $440.00 | Add to Cart |
Calbindin-D, also known as Calbindin 1, is a Vitamin D-dependent cytoplasmic protein in the EF-hand calcium binding protein family that includes calmodulin, parvalbumin, troponin C, and S100. Calbindin-D is widely expressed and regulates calcium homeostasis. Calbindin-D protects neurons from excitotoxic and apoptotic cell death by buffering excess calcium. Human, mouse, and rat Calbindin-D share 99% amino acid sequence identity |
Images
IHC image of neurons staining for the calbindin in the rat cortex. The tissue was fixed with 4% formaldehyde in 0.1 M phosphate buffer, before being removed and prepared for vibratome sectioning.