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| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ul | $303.00 | Add to Cart |
Peripherin is a type III intermediate filament found initially in sensory neurons of the peripheral nervous system (PNS). It serves as a marker for autonomic and sensory neurons in the PNS and motor neurons in the CNS. Peripherin is a diagnostic marker in amyotrophic lateral sclerosis and certain neuronally-derived tumors. Brain injuries can also trigger expression of peripherin and the formation of peripherin accumulations in neurons that are normally silent for this gene. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Autoantibodies to peripherin are also frequently seen in the sera of patients with diabetes. |
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Images
Mixed neuron/glia cultures from newborn rat brain stained with peripherin (green) and phosphorylated NF-H (red). The blue channel reveals the localization of DNA.
Mixed neuron/glia cultures from newborn rat brain stained with peripherin (green) and phosphorylated NF-H (red). The blue channel reveals the localization of DNA.
Western blot of whole rat brain stem homogenate stained with Peripherin at a dilution of 1:20,000. A prominent band running with an apparent SDS-PAGE molecular weight of ~57kDa corresponds to Peripherin. A lower band at ~48kDa is derived from the Peripherin molecule.
Western blot of whole rat brain stem homogenate stained with Peripherin at a dilution of 1:20,000. A prominent band running with an apparent SDS-PAGE molecular weight of ~57kDa corresponds to Peripherin. A lower band at ~48kDa is derived from the Peripherin molecule.