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| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ul | $510.00 | Add to Cart |
100% homology with human and mouse. The biological activities of the neurotrophins are mediated by binding to the different members of the Trk family tyrosine kinase receptors. Three Trk family proteins, TrkA, TrkB and TrkC, exhibiting different ligand specificities, have been identified. At the protein sequence level, Trks are highly conserved between species and the proteins exhibit cross-species activity. Specificity/Sensitivity: Phospho-TrkA (Tyr490) Antibody detects endogenous levels of Trk only when phosphorylated at tyrosine 490. This antibody also detects TrkB and TrkC when phosphorylated at the corresponding residues. |
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Increased mobilization of trkA to neuronal membrane enhances response to NGF challenge. The Journal of Neuroscience, 8 May 2013, 33(19): 8202-8215; doi: 10.1523/JNEUROSCI.4408-12.2013-phospho-TrkA Customer Publications.