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Size | List Price | Price | Cart |
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100 ul | $340.00 | Add to Cart |
Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain. |
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- Product Publications
Product Publications
- Sisi Xu, Peijun Zhang, Meng Zhang, Xin Wang, Gang Li, Gezhi Xu, and Yingqin Ni. (2021). Synaptic Changes and the Response of Microglia in a Light-Induced Photoreceptor Degeneration Model. Molecular Vision, 27:206–220.
- Jagadeesh Kumar Venkatesan, Sivaraman Natarajan, Karin Schwarz, Sabine I. Mayer, Kannan Alpadi, Venkat Giri Magupalli, Ching-Hwa Sung, and Frank Schmitz. Nicotinamide Adenine. (2010). Dinucleotide-Dependent Binding of the Neuronal Ca2+ Sensor Protein GCAP2 to Photoreceptor Synaptic Ribbons. J. Neurosci., 30: 6559 - 6576. doi: 10.1523/JNEUROSCI.3701-09.2010
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Images
Staining of mouse nob rescue retinal sections
Staining of mouse nob rescue retinal sections
Mouse retinal lysates. Courtesy of Megan A. Foreman, University of Birmingham
Mouse retinal lysates. Courtesy of Megan A. Foreman, University of Birmingham
mGluR6 staining of GluR6 in trapezoid body in mouse brain using anti-rabbit Cy3 conjugated secondary antibodies (red color). DAPI was used to counterstain cell nuclei. Dilution 1:30. Tissue was mounted to slide using i-BRITE Plus anti fade media.
mGluR6 staining of GluR6 in trapezoid body in mouse brain using anti-rabbit Cy3 conjugated secondary antibodies (red color). DAPI was used to counterstain cell nuclei. Dilution 1:30. Tissue was mounted to slide using i-BRITE Plus anti fade media.
mGluR6 (green) and protein kinase C (green) staining of P100 rat retinas. (mGluR6 dilution 1:2000). doi: 10.1634
mGluR6 (green) and protein kinase C (green) staining of P100 rat retinas. (mGluR6 dilution 1:2000). doi: 10.1634