BDNF

Brain Derived Growth Factor (BDNF) promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the cns. the versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (ltp), long-term depression (ltd), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

New Testimonial: "I am replying on behalf on Joan Han, who you sent an email to regarding our purchase of BDNF and BDNF CF. We have successfully utilized your BDNF in our experiments. Thank you for checking in." Chiew-Jen Ong, NIH

References:

1. [Brain-derived neurotrophic factor and psychiatric diseases] Tanpakushitsu Kakusan Koso 2007 Jul;52(8):900-5
2. Anterograde transport and secretion of brain-derived neurotrophic factor along sensory axons promote Schwann cell myelination. J Neurosci 2007 Jul 11;27(28):7597-603
3. Repeated co-treatment with imipramine and amantadine induces hippocampal brain-derived neurotrophic factor gene expression in rats. J Physiol Pharmacol 2007 Jun;58(2):219-34
4. Brain-derived neurotrophic factor and TrkB modulate visual experience-dependent refinement of neuronal pathways in retina. J Neurosci 2007 Jul 4;27(27):7256-67
5. A local reduction in cortical GABAergic synapses after a loss of endogenous brain-derived neurotrophic factor, as revealed by single-cell gene knock-out method. J Neurosci 2007 Jul 4;27(27):7234-44
6. Brain-derived neurotrophic factor regulates cholesterol metabolism for synapse development. J Neurosci 2007 Jun 13;27(24):6417-27