Product Details
Catalog Number: MO25042
Applications: WB, IHC, E
Type: Mouse IgG
Immunogen: Residues 140-160 of purified human ApoE (LDLR receptor binding site)-WUE4
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human
Entrez: 348
UniProt: P02649
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ul$325.00Add to Cart

Apolipoprotein E (ApoE) is a major component of specific lipoproteins called very low-density lipoproteins (VLDL). A major function of VLDLs is to remove excess cholesterol from the blood and carry it to the liver for processing. Maintaining normal levels of cholesterol is essential for the prevention of cardiovascular diseases, including heart attacks and strokes. Apolipoprotein E is a type of lipoprotein. Apolipoprotein E is associated with several cardiovascular disorders. There are three isoforms (slightly different forms) of the ApoE lipoprotein. These three isoforms are known as ApoE2, E3, and E4. ApoE2 seems to be one of several genetic factors that play a part in increased risk of heart attacks and strokes and ApoE4 is a risk factor for coronary artery disease. As well, ApoE4 has been suggested to play a role in type 2 Alzheimer disease.

Images
Detection of ApoE in human tissue lysate using NB110-60531.
Lane 1: liver
Lane 2: brain

Detection of ApoE in human tissue lysate using NB110-60531. Lane 1: liver Lane 2: brain

Detection of ApoE in human tissue lysate using NB110-60531.
Lane 1: liver
Lane 2: brain

Detection of ApoE in human tissue lysate using NB110-60531. Lane 1: liver Lane 2: brain

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