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| Size | List Price | Price | Cart |
|---|---|---|---|
| 500,000+ Cells - Frozen | $1,136.40 | Add to Cart |
Human brain microvascular pericytes have many functions including a critical role in the formation and function of the blood-brain barrier, regulation of angiogenses, survival of endothelial cells and phagocytosis of cellular debris. Human Brain Microvascular Perictyes were isolated from normal human brain cortical tissue. Puromycin resistance HBMVPCs are shipped at passage 1 on dry ice in a vial. Pericyte-Growth medium containing 5% fetal bovine serum and growth supplement (PGB001) is recommended for culture. Cells have an average additional population doubling levels >15 when cultured. Cells are prepared and manufactured in an ISO 9001:2015 certified environment and ISO 5 cleanroom. Product Highlights: |
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- Product Publications
Product Publications
- Arshad Hashmat, Jingyuan Ya, Rais Kadir, Mansour Alwjwaj, and Ulvi Bayraktutan. (2024). Hyperglycaemia Perturbs Blood-Brain Barrier Integrity Through Its Effects on Endothelial Cell Characteristics and Function. Tissue Barriers, 2350821. doi: 10.1080/21688370.2024.2350821
- Xin Gao and Ulvi Bayraktutan. (2023). TNF-α Evokes Blood-Brain Barrier Dysfunction through Activation of Rho-Kinase and Neurokinin 1 Receptor. Immunobiology, 228:(5), 152706. doi: 10.1016/j.imbio.2023.152706
- Xin Gao and Ulvi Bayraktutan. (2023). Substance P Reversibly Compromises the Integrity and Function of Blood-Brain Barrier. Peptides, 167: 171048. doi: 10.1016/j.peptides.2023.171048
- Arpan Acharya, Anoop Ambikan, Michellie Thurman, Mohid Reza Malik, Shetty Ravi Dyavar, Akos Vegvari, Ujjwal Neogi, and Siddappa Byrareddy. (2023). Proteomic Landscape of Astrocytes and Pericytes Infected with HIV/SARS-CoV-2 Mono/Co-Infection, Impacting on Neurological Complications. Research Square. doi: 10.21203/rs.3.rs-3031591/v1
- Yvonne Adams, Anne Skovsbo Clausen, Peter Østrup Jensen, Malin Lager, Peter Wilhelmsson, Anna J. Henningson, Per-Eric Lindgren, Daniel Faurholt-Jepsen, Helene Mens, Peter Kraiczy, Kasper Nørskov Kragh, Thomas Bjarnsholt, Andreas Kjaer, Anne-Mette Lebech, and Anja R. Jensen. (2022). 3D Blood-Brain Barrier-Organoids as a Model for Lyme Neuroborreliosis Highlighting Genospecies Dependent Organotropism. iScience. doi: 10.1016/j.isci.2022.105838
- Sorel Kurbegovic, Karina Juhl, Kasper Kildegaard Sorensen, Julie Leth, Gro Linno Willemoe, Anders Christensen, Yvonne Adams, Anja Ramstedt Jensen, Christian Von Buchwald, Jane Skjoth-Rasmussen, Michael Ploug, Knud J. Jensen, Andreas Kjaer. (2021). IRDye800CW Labeled uPAR-Targeting Peptide for Fluorescence-Guided Glioblastoma Surgery: Preclinical Studies in Orthotopic Xenografts. Theranostics, 11(15): 7159-7174. doi: 10.7150/thno.49787
- Yvonne Adams, Rebecca W. Olsen, Anja Bengtsson, Nanna Dalgaard, Mykola Zdioruk, Sanghamitra Satpathi, Prativa K. Behera, Praveen K. Sahu, Sean E. Lawler, Klaus Qvortrup, Samuel C. Wassmer, and Anja T.R. Jensen. (2021). Plasmodium Falciparum Erythrocyte Membrane Protein 1 Variants Induce Cell Swelling and Disrupt the Blood–Brain Barrier in Cerebral Malaria. Journal of Experimental Medicine, 218 (3). doi: 10.1084/jem.20201266
- Ece Bayir, M. Mert Celtikoglu, Aylin Sendemir. (2018). The use of bacterial cellulose as a basement membrane improves the plausibility of the static in vitro blood-brain barrier model. International Journal of Biological Macromolecules. https://doi.org/10.1016/j.ijbiomac.2018.12.257
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Images
Human Brain Pericytes cultured with AlphaBioCoat (AC001)
Human Brain Pericytes cultured with AlphaBioCoat (AC001)
Staining of Actin (dilution 25 ug/mL). Secondary antibody conjugated to Alexa 594 (red) and counterstained with DAPI (blue). Cell were mounted using iBrite mounting media.
Staining of Actin (dilution 25 ug/mL). Secondary antibody conjugated to Alexa 594 (red) and counterstained with DAPI (blue). Cell were mounted using iBrite mounting media.
Staining of Desmin (dilution 1:100). Secondary antibody conjugated to Alexa 594 (red) and counterstained with DAPI (blue). Cell were mounted using iBrite mounting media.
Staining of Desmin (dilution 1:100). Secondary antibody conjugated to Alexa 594 (red) and counterstained with DAPI (blue). Cell were mounted using iBrite mounting media.
Staining of VWF/Factor VIII (dilution 1:100). Secondary antibody conjugated to Alexa 594 (red) and counterstained with DAPI (blue). Cell were mounted using iBrite mounting media.
Staining of VWF/Factor VIII (dilution 1:100). Secondary antibody conjugated to Alexa 594 (red) and counterstained with DAPI (blue). Cell were mounted using iBrite mounting media.