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Product Sizes
| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ug | $365.00 | Add to Cart |
Members of the semaphorin protein family are involved in axonal guidance during neural development. Semaphorin 5a is thought to have a bifunctional role in axon guidance, exerting both attractive and inhibitory effects on developing axons associated with limbic function. The thrombospondin repeats of Semaphorin 5a physically interact with both heparan sulfate proteoglycans and chondroitin sulfate proteoglycans, inducing attractive and inhibitory guidance cues, respectively. The biological responses to Semaphorin 5a are induced through binding to its high-affinity receptor, plexin B3, triggering intracellular signaling through Me Semaphorine 5A plays a role in autism, reducing the ability of neurons to form connections with other neurons in certain brain regions |
Supporting Products
| Name | Catalog # | Size |
|---|---|---|
| Semaphorin 5A | P41026 | 100 ug Blocking Peptide |
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Images
Semaphorin5a (dilution: 2.5 µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining Protocol on Data-sheet.
Semaphorin5a (dilution: 2.5 µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining Protocol on Data-sheet.