Product Details
Catalog Number: GT41025
Applications: IHC
Type: Goat IgG
Dilutions: IHC 2-15 ug/mL; WB 0.1-0.2 ug/mL; E 0.5-1.0 ug/mL
Immunogen: Peptide with sequence TTLAGAVPRMM-C, from the N Terminus of the protein sequence according to NP_000429.2; NP_039230.1; NP_852122.1;.1 NP_852123.1; NP_852124.1; NP_852125.1; NP_852126.1.
Storage: Antibody can be aliquotted and stored frozen at -20° C to -70° C in a manual defrost freezer for six months without detectable loss of activity. The antibody can be stored at 2° - 8° C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 5077
UniProt: P23760
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$365.00Add to Cart

PAX3 is a member of the paired box (PAX) family of transcription factors. It is a critical factor for the proper formation of the mammalian nervous, cardiovascular, and muscular systems.

Mutations in Pax3 resulting in complete loss of function have provided important models for the study of neural tube defects, congenital cardiac diseases affecting the outflow tract of the heart, and for the elucidation of the genetic pathways regulating myogenesis. In humans, haploinsufficiency of PAX3 results in deafness, pigmentation defects, and other neural crest-related abnormalities as well as variable-limb myopathy.

Note: This antibody is expected to recognise all 7 reported human isoforms (as represented by NP_000429.2; NP_039230.1; NP_852122.1;.1 NP_852123.1; NP_852124.1; NP_852125.1 and NP_852126.1).

Supporting Products
NameCatalog #Size
PAX3P41025100 ug Blocking Peptide
Images
PAX3 (dilution: 3.0 µg/ml) staining of paraffin embedded Human Esophagus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

PAX3 (dilution: 3.0 µg/ml) staining of paraffin embedded Human Esophagus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

PAX3 (dilution: 3.0 µg/ml) staining of paraffin embedded Human Esophagus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

PAX3 (dilution: 3.0 µg/ml) staining of paraffin embedded Human Esophagus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

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