Product Details
Product Sizes
Size | List Price | Price | Cart |
---|---|---|---|
100 ug | $365.00 | Add to Cart |
Corticotropin Releasing Hormone Receptor 1 (CRHR1 or CRF1) is a member of the corticotropin-releasing factor family of G-protein-coupled receptors that also includes CRF2. It is abundantly expressed in the CNS with major expression in the cortex, cerebellum, hippocampus, amygdala, olfactory bulb and pituitary. In the periphery, the receptors are expressed at low levels in the skin, ovary, testis and adrenal gland. It mediates stress and anxiety including stress related colonic motor activity. |
Supporting Products
Name | Catalog # | Size |
---|---|---|
Corticotropin Releasing Hormone Receptor 1 | P41006 | 100 ug Blocking Peptide |
Images
CRF1 (dilution: 0.3µg/ml) staining in green a dendrite of a neuronal cell in C57 mouse cortex. Counter-stained with DAPI (in blue). Courtesy of Dr Y. Chen, TZ Baram lab, UC Irvine, CA
CRF1.(Dilution 0.1µg/ml) staining of human colon lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.