Product Details
Product Sizes
| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ug | $365.00 | Add to Cart |
Alsin2 specifically binds to, and functions as a guanine nucleotide exchange factor (GEF) for the small GTPase RAB5. It contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. |
Supporting Products
| Name | Catalog # | Size |
|---|---|---|
| Alsin/ALS2 | P41001 | 100 ug Blocking Peptide |
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Images
Alsin (dilution: 3.8µg/ml) staining of human brain tissue, cortex (formalin-fixed paraffin-embedded) at 5 ug/ml followed by biotinylated horse anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Protocol on data-sheet.
Alsin (dilution: 3.8µg/ml) staining of human brain tissue, cortex (formalin-fixed paraffin-embedded) at 5 ug/ml followed by biotinylated horse anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Protocol on data-sheet.