Product Details
Product Sizes
| Size | List Price | Price | Cart |
|---|---|---|---|
| 12 well | $3,369.60 | Add to Cart | |
| 24 well | $4,698.00 | Add to Cart | |
| 6 well | $2,306.88 | Add to Cart |
Human BBB is available only to US customers Our model mimic transport properties of the Blood Brain Barrier (BBB) due to the formation of tight junctions, higher expression of specific carriers, or great cell viability. We developed a 3D in vitro model of the BBB by culturing brain endothelial cells with pericytes and astrocytes layered in an insert. This model improves endothelial cell polarization and enhances the formation of tight junctions, provide better endothelial cell-to-cell contact that is important for barrier development, and prevent the dilution of secreted neurotrophic factors, and these conditions collectively led to the development of an in vitro model that can truly mimic the BBB. Models are made to order. Please allow 4-8 weeks for completion. Models come with media. Additional media can be ordered (catalog # NMBBB01). BBB model can be used for transport and permeability studies from ions to macromolecules. Models are prepared and manufactured in an ISO 9001:2015 certified environment and ISO 5 cleanroom. Product Highlights: |
Images
ACE-2 staining (red) and DAPI nuclear counterstain (blue) of the endothelial cells on the bottom of the inserts. Images collected on a microscope.
Diagram of BBB Model Insert
A demonstration of how to measure TEER. Shown using a control plate.