Since their introduction, our Human Brain Microvascular Endothelial Cells (HBMECs) (cat. HEC02) have been one of our most popular cell types. In the past two years alone, they've been utilized in published glioblastoma, cerebral cavernous malformation (CCM), diabetes, and COVID-19 research. We encourage you to check out all publications using these cells here.
Image: HBMECs stained with Claudin-5
And now, this past month, our HBMECs were cited in newly published hypertension research. Researchers from Albert Einstein College of Medicine were investigating miR-4432, a small nucleic acid, as an inhibitor to fibroblast growth factor binding protein 1 in HBMECs. They found that miR-4432 reduces endothelial oxidative stress, which is a key feature of hypertension. They suggest miR-4432 to be further studied to better understand its role in endothelial dysfunction. Read the full publication here.
In addition to our HBMECs, Neuromics offers an impressive selection of other research proven human endothelial cells, including retinal (cat. HEC09), umbilical vein (cat. HEC01), and more. Explore all our endothelial cells here and the ways they've been used.
Beyond endothelial cells, we have a further assortment of human cells & tissue. This includes our immortalized human brain microglia (cat. HBMCs001), which were highlighted in our most recent blog post (learn more). You can find all our human cells here.