TRPV1 (VR1)

Catalog Number: RA10110

1. Kuang-Yi Tseng, Hung-Chen Wang, Yi-Hsuan Wang, Miao-Pei Su, Kai-Feng Cheng, Kuang-I Cheng, and Lin-Li Chang. (2023). Peripheral Nerve Denervation in Streptozotocin-Induced Diabetic Rats Is Reduced by Cilostazol. Medicina, 59(3), 553. doi: 10.3390/medicina59030553
2. David D. Kline, Sheng Wang, and Diana L. Kunze. (2019). TrpV1 channels contribute to spontaneous glutamate release in nucleus tractus solitarius (nTS) following chronic intermittent hypoxia (CIH). Journal of Neurophysiology. https://doi.org/10.1152/jn.00536.2018
3. Yu S.-Q., Ma S., Wang D.H. (2018). Activation of TRPV1 Prevents Salt-Induced Kidney Damage and Hypertension After Renal Ischemia-Reperfusion Injury in Rats. Kidney and Blood Pressure Research, Vol. 43, No. 4, pg. 1285-1296. Doi: 10.1159/000492412
4. Yang Yu, Xini Huang, Yuwei Di, Lintao Qu & Ni Fan. (2017). Effect of CXCL12/CXCR4 signaling on neuropathic pain after chronic compression of dorsal root ganglion. Scientific Reports, 7, Article number: 5707. doi: 10.1038/s41598-017-05954-1
5. Marina Quartu,Maria Pina Serra,Marianna Boi,Laura Poddighe, Cristina Picci,Roberto Demontis,and Marina Del Fiacco. (2016). TRPV1 receptor in the human trigeminal ganglion and spinal nucleus: immunohistochemical localization and comparison with the neuropeptides CGRP and SP. Journal of Anatomy, doi: 10.1111/joa.12529
6. Krisztina Pohóczky, József Kun, Bálint Szalontai, Éva Szőke, Éva Sághy, Maja Payrits, Béla Kajtár, Krisztina Kovács, József László Környei, János Garai, András Garami, Anikó Perkecz, Levente Czeglédi and Zsuzsanna Helyes. (2015). Oestrogen-dependent up-regulation of TRPA1 and TRPV1 receptor proteins in the rat endometrium. J Mol Endocrinol, doi: 10.1530/JME-15-0184
7. Souichi Kokubun, Tadasu Sato, Chikara Ogawa, Kai Kudo, Koju Goto, Yuki Fujii, Yoshinaka Shimizu, Hiroyuki Ichikawa. (2015). Distribution of TRPV1 and TRPV2 in the human stellate ganglion and spinal cord. Neuroscience Letters, doi: 10.1016/j.neulet.2015.01.074
8. Cai-hua Wu, Zheng-tao Lv, Yin Zhao, Yan Gao, Jia-qing Li, Fang Gao, Xian-fang Meng, Bo Tian, Jing Shi, Hui-lin Pan and Man Li. (2013). Electroacupuncture improves thermal and mechanical sensitivities in a rat model of postherpetic neuralgia. Molecular Pain, 9:18. doi: 10.1186/1744-8069-9-18
9. J.L. Saloman, M.-K. Chung, J.Y. Ro. (2013). P2X3 and TRPV1 functionally interact and mediate sensitization of trigeminal sensory neurons. Neuroscience, Volume 232, Pages 226-238. doi: 10.1016/j.neuroscience.2012.11.015
10. Leanne M. Ramer, A. Peter van Stolk, Jessica A. Inskip, Matt S. Ramer and Andrei V. Krassioukov. (2012). Plasticity of TRPV1-expressing sensory neurons mediating autonomic dysreflexia following spinal cord injury. Frontiers in Physiology, doi: 10.3389/fphys.2012.00257
11. Lee, Jongseok; Saloman, Jami L.; Weiland, Gustave; Auh, Q-Schick; Chung, Man-Kyo; Ro, Jin Y. (2012). Functional interactions between NMDA receptors and TRPV1 in trigeminal sensory neurons mediate mechanical hyperalgesia in the rat masseter muscle. PAIN, 153 (7), p.1514-1524. doi: 10.1016/j.pain.2012.04.015
12. Lintao Qua, Pu Zhang, Robert H. LaMotte and Chao Ma. (2011). Neuronal Fc-gamma receptor I mediated excitatory effects of IgG immune complex on rat dorsal root ganglion neurons. Brain, Behavior, and Immunity, doi: 10.1016/j.bbi.2011.04.008
13. T. Wu, L. Song, X. Shi, Z. Jiang, J. Santos-Sacchi and A.L. Nuttal. (2011). Effect of capsaicin on potassium conductance and electromotility of guinea pig outer hair cell. Hearing Research, doi: 10.1016/j.heares.2010.10.010
14. Muthu D. Bhaskaran and Bret N. Smith. (2010). Effects of TRPV1 activation on synaptic excitation in the dentate gyrus of a mouse model of temporal lobe epilepsy. Experimental Neurology, doi: 10.1016/j.expneurol.2010.01.021
15. Sonia K Bhangoo, Matthew S Ripsch, David J Buchanan, Richard J Miller and Fletcher A White. (2009). Increased chemokine signaling in a model of HIV1-associated peripheral neuropathy. Molecular Pain, 5:48. doi: 10.1186/1744-8069-5-48
16. Sacha A. Malin, Julie A. Christianson, Klaus Bielefeldt, and Brian M. Davis. (2009). TPRV1 Expression Defines Functionally Distinct Pelvic Colon Afferents. J. Neurosci., 29. doi: 10.1523/JNEUROSCI.3791-08.2009
17. Sefika C Mizrak, Bart M Gadella, Hatice Erdost, Aytekin Ozer, Ana MM van Pelt, Federica MF van Dissel-Emiliani. (2008). Spermatogonial stem cell sensitivity to capsaicin: An in vitro study. Reproductive Biology and Endocrinology, 6:52, 743 - 752. doi: 10.1186/1477-7827-6-52
18. Alexander T. Stein, Carmen A. Ufret-Vincenty, Li Hua, Luis F. Santana, and Sharona E. Gordon. (2006). Phosphoinositide 3-Kinase Binds to TRPV1 and Mediates NGF-stimulated TRPV1 Trafficking to the Plasma Membrane. The Journal of General Physiology, doi: 10.1085/jgp.200609576
19. Sharif Naeini R, Witty MF, Seguela P, Bourque CW. (2006). An N-terminal variant of Trpv1 channel is required for osmosensory transduction. Nature Neuroscience, (1):93-8. doi: 10.1038/nn1614
20. Aoki Y, Ohtori S, Takahashi K, Ino H, Douya H, Ozawa T, Saito T, and Moriya H. (2005). Expression and Co-Expression of VR1, CGRP, and IB4-Binding Glycoprotein in Dorsal Root Ganglion Neurons in Rats: Differences Between the Disc Afferents and the Cutaneous Afferents. Spine, 30(13):1496-1500. doi: 10.1097/01.brs.0000167532.96540.31
21. Labrakakis C, Tong C, Weissman T, Torsney C and MacDermott A. (2003). Localization and function of ATP and GABAA receptors expressed by nociceptors and other postnatal sensory neurons in rat. J Physiol, 549(1):131-142. doi: 10.1113/jphysiol.2002.031963
22. Liapi A, and Wood JN. (2005). Extensive co-localization and heteromultimer formation of the vanilloid receptor-like protein TRPV2 and the capsaicin receptor TRPV1 in the adult rat cerebral cortex. Eur J Neurosci, 22(4):825. doi: 10.1111/j.1460-9568.2005.04270.x
23. Nakatsuka T, Tsuzuki K, Ling JX, Sonobe H and Gu JG. (2003). Distinct Roles of P2X Receptors in Modulating Glutamate Release at Different Primary Sensory Synapses in Rat Spinal Cord. J Neurophys, 89: 3243-3252. doi: 10.1152/jn.01172.2002
24. Rosenbaum T, Awaya M, and Gordon SE. (2002). Subunit modification and association in VR1 ion channels. BMC Neurosci, 3:4. doi: 10.1186/1471-2202-3-4
25. Zahner MR, Li DP, Chen SR, and Pan HL. (2003). Cardiac vanilloid receptor 1-expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats. J Physiol, 551(2):515-523. doi: 10.1113/jphysiol.2003.048207
26. Zimov S and Yazulla S. (2004). Localization of vanilloid receptor 1 (TRPV1/VR1)-like immunoreactivity in goldfish and zebrafish retinas: Restriction to photoreceptor synaptic ribbons. J Neurocytol, 33:441–452. doi: 10.1007/s11068-004-4209-3
27. Zwick M, Davis BM, Woodbury CJ, Burkett JH, Koerber HR, Simpson JF, and Albers KM. (2002). Glial Cell Line-Derived Neurotrophic Factor is a Survival Factor for Isolectin B4-Positive, but not Vanilloid Receptor 1-Positive, Neurons in the Mouse. J Neurosci, 22(10):4057-4065.

Catalog Number: RA14113

1. Md Nabiul Islam, Naoki Maeda, Emi Miyasato, Mir Rubayet Jahan, Abu Md Mamun Tarif, Taiga Ishino, Kanako Nozaki, Koh-Hei Masumoto, Akie Yanai, and Koh Shinoda. (2020). Expression of Huntingtin-Associated Protein 1 in Adult Mouse Dorsal Root Ganglia and its Neurochemical Characterization in Reference to Sensory Neuron Subpopulations. IBRO Reports, 9, 258-269. doi: 10.1016/j.ibror.2020.10.001
2. Rahul Atmaramani. (2020). Development of an in vitro Phenotypic Assay for Screening Chronic Pain Therapeutics. University of Texas at Dallas, Doctoral Dissertation.
3. Helen Kühn, Leonie Kappes, Katharina Wolf, Lisa Gebhardt, Markus F. Neurath, Peter Reeh, Michael J. M. Fischer, and Andreas E. Kremer. (2020). Complementary Roles of Murine Na V 1.7, Na V 1.8 and Na V 1.9 in Acute Itch Signalling. Scientific Reports, 10:2326. doi: 10.1038/s41598-020-59092-2
4. Fengxian Li, Weishan Yang, Haowu Jiang, Changxiong Guo, Andrew J. W. Huang, Hongzhen Hu & Qin Liu (2019). TRPV1 activity and substance P release are required for corneal cold nociception. Nature Communications. https://doi.org/10.1038/s41467-019-13536-0
5. Poitras, T., Chandrasekhar, A., McCoy, L. et al. (2019). Selective Sensory Axon Reinnervation and TRPV1 Activation. Mol Neurobiol https://doi.org/10.1007/s12035-019-1574-6
6. Maria Cristina Marrone, Annunziato Morabito, Michela Giustizieri, Valerio Chiurchiù, Alessandro Leuti, Marzia Mattioli, Sara Marinelli, Loredana Riganti, Marta Lombardi, Emanuele Murana, Antonio Totaro, Daniele Piomelli, Davide Ragozzino, Sergio Oddi, Mauro Maccarrone, Claudia Verderio & Silvia Marinelli. (2017). TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice. Nature Communications, 8, Article number: 15292. doi: 10.1038/ncomms15292
7. Danyou Hu, Changming Wang, Fengxian Li, et al. (2017). “A Combined Water Extract of Frankincense and Myrrh Alleviates Neuropathic Pain in Mice via Modulation of TRPV1,” Neural Plasticity, vol. 2017, Article ID 3710821, 11 pages. doi: 10.1155/2017/3710821
8. Changming Wang, Zhongli Wang, Yan Yang, Chan Zhu, Guanyi Wu, Guang Yu, Tunyu Jian, Niuniu Yang, Hao Shi, Min Tang, Qian He, Lei Lan, Qin Liu, Yun Guan, Xinzhong Dong, Jinao Duan and Zongxiang Tang. (2015). Pirt contributes to uterine contraction-induced pain in mice. Molecular Pain, 11:57. doi: 10.1186/s12990-015-0054-x
9. Carl Weitlauf, Nicholas J. Ward, Wendi S. Lambert, Tatiana N. Sidorova, Karen W. Ho, Rebecca M. Sappington, and David J. Calkins. (2014). Short-Term Increases in Transient Receptor Potential Vanilloid-1 Mediate Stress-Induced Enhancement of Neuronal Excitation. The Journal of Neuroscience, 34(46): 15369-15381. doi: 10.1523/JNEUROSCI.3424-14.2014
10. Marics I, Malapert P, Reynders A, Gaillard S, Moqrich A. (2014). Acute Heat-Evoked Temperature Sensation Is Impaired but Not Abolished in Mice Lacking TRPV1 and TRPV3 Channels. PLoS ONE, 9(6): e99828. doi: 10.1371/journal.pone.0099828
11. Dongyue Huang, Shuyang Li, Ajay Dhaka, Gina M Story and Yu-Qing Cao. (2012). Expression of the transient receptor potential channels TRPV1, TRPA1 and TRPM8 in mouse trigeminal primary afferent neurons innervating the dura. Molecular Pain, 8:66. doi: 10.1186/1744-8069-8-66
12. Sarah E. Canetta, Edlira Luca, Elyse Pertot, Lorna W. Role,  David A. Talmage. (2011). Type III Nrg1 Back Signaling Enhances Functional TRPV1 along Sensory Axons Contributing to Basal and Inflammatory Thermal Pain Sensation. PLoS ONE, 6(9): e25108. doi: 10.1371/journal.pone.0025108
13. Julie A. Christianson, Klaus Bielefeldt, Sacha A. Malin and Brian M. Davis. (2010). Neonatal colon insult alters growth factor expression and TRPA1 responses in adult mice. Pain, Volume 151, Issue 2, Pages 540-549. doi: 10.1016/j.pain.2010.08.029
14. Kenjiro Matsumoto, Emi Kurosawa, Hiroyuki Terui, Takuji Hosoya, Kimihito Tashima, Toshihiko Murayama, John V Priestley, and Syunji Horie. (2009). Localization of TRPV1 and contractile effect of capsaicin in mouse large intestine: high abundance and sensitivity in rectum and distal colon. Am J Physiol Gastrointest Liver Physiol, doi: 10.1152/ajpgi.90578.2008
15. Rebecca M. Sappington, Tatiana Sidorova, Daniel J. Long, and David J. Calkins. (2009). TRPV1: Contribution to Retinal Ganglion Cell Apoptosis and Increased Intracellular Ca2+ with Exposure to Hydrostatic Pressure. Invest. Ophthalmol. Vis. Sci., 50: 717 - 728. doi: 10.1167/iovs.08-2321
16. Ann M. Bode, Yong-Yeon Cho, Duo Zheng, Feng Zhu, Marna E. Ericson, Wei-Ya Ma, Ke Yao, and Zigang Dong. (2009). Transient Receptor Potential Type Vanilloid 1 Suppresses Skin Carcinogenesis. Cancer Res., 69: 905 - 913. doi: 10.1158/0008-5472.CAN-08-3263
17. Jens Hjerling-Leffler, Mona AlQatari,  Patrik Ernfors, and Martin Koltzenburg. (2007). Emergence of Functional Sensory Subtypes as Defined by Transient Receptor Potential Channel Expression. The Journal of Neuroscience, 27(10):2435–2443. doi: 10.1523/JNEUROSCI.5614-06.2007

Catalog Number: GP14100

1. Madoka Koyanagi, Ryosuke Ogido, Akari Moriya, Mamiko Saigo, Satoshi Ihida, Tomoko Teranishi, Jiro Kawada, Tatsuya Katsuno, Kazuo Matsubara, Tomohiro Terada, Akira Yamashita, and Satoshi Imai. (2024). Development of a 3-Dimensional Organotypic Model with Characteristics of Peripheral Sensory Nerves. Cell Reports Methods. doi: 10.1016/j.crmeth.2024.100835
2. Tomoki Yamaguchi, Siamak Salavatian, Yuki Kuwabara, Abigail Hellman, Bradley K. Taylor, Kimberly Howard-Quijano, and Aman Mahajan. (2023). Thoracic Dorsal Root Ganglion Application of Resiniferatoxin Reduces Myocardial Ischemia-Induced Ventricular Arrhythmias. Biomedicines, 11, 2720. doi: 10.3390/biomedicines11102720
3. Erick J. Rodrıguez-Palma, Yarim E. De la Luz-Cuellar, Ana M. Islas-Espinoza, Adalberto E. Felix-Leyva, Stephanie I. Shiers, Guadalupe Garcıa, Jorge E. Torres-Lopez, Rodolfo Delgado-Lezama, Janet Murbartian, Theodore J. Price, and Vinicio Granados-Soto. (2023). Activation of a6-Containing GABAA Receptors Induces Antinociception Under Physiological and Pathological Conditions. Pain, 164(5), 948–966. doi: 10.1097/j.pain.0000000000002763
4. Tarek Ibrahim, Ping Wu, Li-Ju Wang, Alexei Tumanov, Zhao Lai, Korri Weldon, Yidong Chen, and Shivani Rupare. (2023). Sex-Dependent Differences in the Genomic Profile of Lingual Sensory Neurons in Naïve and Tongue Tumor Bearing Mice. bioRxiv. doi: 10.1101/2023.01.14.524011
5. Kensho Kanehisa, Keisuke Koga, Sho Maejima, Yuto Shiraishi, Konatsu Asai, Miho Shiratori-Hayashi, Mei-Fang Xiao, Hirotaka Sakamoto, Paul F. Worley, and Makoto Tsuda. (2022). Neuronal Pentraxin 2 Is Required for Facilitating Excitatory Synaptic Inputs onto Spinal Neurons Involved in Pruriceptive Transmission in a Model of Chronic Itch. Nature Communications, 13:2367. doi: 10.1038/s41467-022-30089-x
6. Judit Rosta, Mate Toth, Nadine Friedrich, Peter Santha, Gabor Jancso, and Maria Dux. (2022). Insulin Sensitizes Neural and Vascular TRPV1 Receptors in the Trigeminovascular System. The Journal of Headache and Pain, 23(7). doi: 10.1186/s10194-021-01380-x
7. Abraham B. Beckers, Ellen Wilms, Zlatan Mujagic, Béla Kajtár, Kata Csekő, Zsa Zsa R. M. Weerts, Lisa Vork, Freddy J. Troost, Joanna W. Kruimel, José M. Conchillo, Zsuzsanna Helyes, Ad A. M. Masclee, Daniel Keszthelyi, and Daisy M. A. E. Jonkers. (2021). Age-Related Decrease in Abdominal Pain and Associated Structural- and Functional Mechanisms: An Exploratory Study in Healthy Individuals and Irritable Bowel Syndrome Patients. Frontiers in Pharmacology. doi: 10.3389/fphar.2021.806002
8. Xiaodong Yan, Sitao Zhang, Haiyan Zhao, Ping Liu, Haixia Huang, Weizhen Niu, Wei Wang, and Chen Zhang. (2021). ASIC2 Synergizes with TRPV1 in the Mechano-Electrical Transduction of Arterial Baroreceptors. Neuroscience Bulletin. doi: 10.1007/s12264-021-00737-1
9. Qing-Tao Meng, Xian-Yu Liu, Xue-Ting Liu, Devin M. Barry, Hua Jin, Yu Sun, Qianyi Yang, Li Wan, Jin-Hua Jin, Kai-Feng Shen, Admire Munanairi, Ray Kim, Jun Yin Ailin Tao, and Zhou-Feng Chen. (2021). BNP Facilitates NMB-Mediated Histaminergic Itch via NPRC-NMBR Crosstalk. bioRxiv. doi: 10.1101/2021.01.26.428310
10. Seol-Hee Kim, Parmvir K. Bahia, Mayur Patil, Sydney Sutton, Isobel Sowells, Stephen H. Hadley, Marian Kollarik, and Thomas E. Taylor-Clark. (2020). Development of a Mouse Reporter Strain for the Purinergic P2X2 Receptor. eNeuro. doi: 10.1523/ENEURO.0203-20.2020
11. Devin M. Barry, Xue-Ting Liu, Benlong Liu, Xian-Yu Liu, Fang Gao, Xiansi Zeng, Juan Liu, Qianyi Yang, Steven Wilhelm, Jun Yin, Ailin Tao, and Zhou-Feng Chen. (2020). Exploration of Sensory and Spinal Neurons Expressing Gastrin-Releasing Peptide in Itch and Pain Related Behaviors. Nature Communications, 11:1397. doi: 10.1038/s41467-020-15230-y
12. Yoshie Umehara, Sumika Toyama, Mitsutoshi Tominaga, Hironori Matsuda, Nobuaki Takahashi, Yayoi Kamata, François Niyonsaba, Hideoki Ogawa, and Kenji Takamori. (2020). Robust Induction of Neural Crest Cells to Derive Peripheral Sensory Neurons from Human Induced Pluripotent Stem Cells. Scientific Reports, 10:4360. doi: 10.1038/s41598-020-60036-z
13. Nan-Qi Lia, Yang Tang, Si-Ting Huang, Xue-Ting Liu, Li-Ping Zeng, Hui Li, and Li Wan. (2020). Modulation of NR1 Receptor By CaMKIIα Plays an Important Role in Chronic Itch Development in Mice.  Brain Research Medium. doi: 10.1016/j.brainresbull.2020.02.011
14. Seol-Hee Kim, Stephen H Hadley, Mikayla Maddison, Mayur Patil, Byeong Cha, Marian Kollarik, and Thomas E Taylor-Clark. (2020). Mapping of Sensory Nerve Subsets Within the Vagal Ganglia and the Brainstem Using Reporter Mice for Pirt, TRPV1, 5HT3, and Tac1 Expression. eNeuro. doi: 10.1523/ENEURO.0494-19.2020

15. Sho Kato, Hiroki Wakabayashi , Taro Nakagawa, Gaku Miyamura, Yohei Naito, Takahiro Iino, Akihiro Sudo (2019). Teriparatide improves pain-related behavior and prevents bone loss in ovariectomized mice. Journal of Orthopaedic Surgery.  https://doi.org/10.1177/2309499019893194

16. Shijin Xuab, Yan Xu, Xueying Cheng, Cheng Huang, Yonglu Pan, Shiyun Jin, Wei Xiong, Li Zhang, Shufang He, Ye Zhang. (2019). Inhibition of DRG-TRPV1 upregulation in myocardial ischemia contributes to exogenous cardioprotection. Journal of Molecular and Cellular Cardiology. https://doi.org/10.1016/j.yjmcc.2019.12.003

17. Dorte X. Gram, Josefine Fribo, Istvan Nagy, Carsten Gotfredsen, Ana Charrua, John B. Hansen, Anker J. Hansen, Arpad Szallasi. (2019). TRPV1 Antagonists as Novel Anti-Diabetic Agents: Regulation of Oral Glucose Tolerance and Insulin Secretion Through Reduction of Low-Grade Inflammation? Medical Sciences, 7, 82. doi: 10.3390/medsci7080082

18. M. Patil, A.H. Hovhannisyan, A. Wangzhou, J. Mecklenburg, W. Koek, V. Goffin, D. Grattan, U. Boehm, G. Dussor, T.J. Price, A.N. Akopian. (2019). Prolactin Receptor Expression in Mouse Dorsal Root Ganglia Neuronal Subtypes Is Sex-Dependent. Journal of Neuroendocrinology. doi: 10.1111/jne.12759

19. Silvia Gutierrez, P Abigail Alvarado-Vazquez, James C Eisenach, E Alfonso Romero-Sandoval, and M Danilo Boada. (2019). Tachykinins modulate nociceptive responsiveness and sensitization: In vivo electrical characterization of primary sensory neurons in tachykinin knockout (Tac1 KO) mice. Molecular Pain Volume 15: 1–16. DOI: 10.1177/1744806919845750

20. Vicki J Swier, Katherine White, David K Meyerholz, Aude Chefdeville, Rajesh Khanna, Jessica C Sieren, Dawn E Quelle, Jill M Weimer (2019). Validating indicators of CNS disorders in a swine model of neurological disease. bioRxiv 514398; doi: https://doi.org/10.1101/514398
21. Taro Nakagawa, Hiroki Wakabayashi, Yohei Naito, Sho Kato, Gaku Miyamura, Takahiro Iino, Akihiro Sudo. (July 4, 2018). The effects of bisphosphonate on pain-related behavior and immunohistochemical analyses in hindlimb-unloaded mice. Journal of Orthopaedic Science. https://doi.org/10.1016/j.jos.2018.06.002.
22. Mayur J. Patil, Anahit H. Hovhannisyan, Armen N. Akopian. Characteristics of sensory neuronal groups in CGRP-cre-ER reporter mice: Comparison to Nav1.8-cre, TRPV1-cre and TRPV1-GFP mouse lines. Published: June 4, 2018https://doi.org/10.1371/journal.pone.0198601
23. Paulino Barragán-Iglesias, Tzu-Fang Lou, Vandita D. Bhat, Salim Megat, Michael D. Burton, Theodore J. Price & Zachary T. Campbell. (2018). Inhibition of Poly(A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice. Nature Communications 9, Article number: 10 doi:10.1038/s41467-017-02449-5
24. Charles A. Warwick. (2017). The role of complement component C5a in nociceptive sensitization. Theses and Dissertations. University of Iowa
25. Noémi Bohonyi, Krisztina Pohóczky, Bálint Szalontai, Anikó Perkecz, Krisztina Kovács, Béla Kajtár, Lajos Orbán, Tamás Varga, Sarolta Szegedi, József Bódis, Zsuzsanna Helyes, Miklós Koppán. (2017). Local upregulation of transient receptor potential ankyrin 1 and transient receptor potential vanilloid 1 ion channels in rectosigmoid deep infiltrating endometriosis. Molecular Pain, doi: 10.1177/1744806917705564
26. Chen J, Varga A, Selvarajah S, Jenes A, Dienes B, Sousa-Valente J, Kulik A, Veress G, Brain SD, Baker D, Urban L, Mackie K, Nagy I. (2016). Spatial Distribution of the Cannabinoid Type 1 and Capsaicin Receptors May Contribute to the Complexity of Their Crosstalk. Sci Rep., doi: 10.1038/srep33307
27. Sarah Krupp. (2016). Effects of neonatal capsaicin on formalin-induced ATF3 expression in the adult rat. The University of Louisville's Institutional Repository Electronic Theses and Dissertations.
28. Obadah N. Austah, Nikita B. Ruparel, Michael A. Henry, Roberto J. Fajardo, James E. Schmitz, & Anibal Diogenes. (2016). Capsaicin-sensitive Innervation Modulates the Development of Apical Periodontitis. Journal of Endodontics, doi: 10.1016/j.joen.2016.06.009
29. Elaine D. Por, Jae-Hyek Choi & Brian J. Lund. (2015). Low-Level Blast Exposure Increases Transient Receptor Potential Vanilloid 1 (TRPV1) Expression in the Rat Cornea. Current Eye Research, doi: 10.3109/02713683.2015.1122812
30. Mruvil Abooj, Mahendra Bishnoi, Christine A. Bosgraaf and Louis S. Premkumar. (2016). Changes in Spinal Cord Following Inflammatory and Neuropathic Pain and the Effectiveness of Resiniferatoxin. The Open Pain Journal, 9, 1-14. doi: 10.2174/1876386301609010001
31. Erin M. Boisvert, Sandra J. Engle, Shawn E. Hallowell, Ping Liu, Zhao-Wen Wang & Xue-Jun Li. (2015). The Specification and Maturation of Nociceptive Neurons from Human Embryonic Stem Cells. Scientific Reports, 5, Article number: 16821. doi: 10.1038/srep16821
32. Xue-Long Wang, Bin Tian, Ya Huang, Xiao-Yan Peng, Li-Hua Chen, Jun-Cheng Li & Tong Liu. (2015). Hydrogen sulfide-induced itch requires activation of Cav3.2 T-type calcium channel in mice. Scientific Reports, 5, Article number: 16768. doi: 10.1038/srep16768
33. Pourtau L, Heeringa AN, Rovere C, Aubert A, Nahon JL, Miraux S, Konsman JP. (2014). Increased circulating rather than spinal cytokines accompany chronic pain behaviors in experimental bone cancer and arthritis. Neuroimmunology and Neuroinflammation, 1:153-60. doi: 10.4103/2347-8659.143680
34. S Kelly, R J Chapman, S Woodhams, D R Sagar, J Turner, J J Burston, C Bullock, K Paton, J Huang, A Wong, D F McWilliams, B N Okine, D A Barrett, G J Hathway, D A Walsh, V Chapman. (2013). Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain. Ann Rheum Dis, doi: 10.1136/annrheumdis-2013-203413
35. M. Shukla, R. Quirion, W. Ma. (2013). Reduced expression of pain mediators and pain sensitivity in amyloid precursor protein over-expressing CRND8 transgenic mice. Neuroscience, Volume 250, Pages 92–101. doi: 10.1016/j.neuroscience.2013.06.064
36. Dustin Green, Shivani Ruparel, Linda Roman, Michael A. Henry, Kenneth M. Hargreaves. (2013). Role of Endogenous TRPV1 Agonists in a Post-Burn Pain Model of Partial-Thickness Injury. PAIN, doi: 10.1016/j.pain.2013.07.040
37. Tong Liu, Temugin Berta, Zhen-Zhong Xu, Chul-Kyu Park, Ling Zhang, Ning Lü, Qin Liu, Yang Liu, Yong-Jing Gao, Yen-Chin Liu, Qiufu Ma, Xinzhong Dong, and Ru-Rong Ji. (2012). TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice. J Clin Invest., 122(6): 2195–2207. doi: 10.1172/JCI45414
38. Iryna A. Khasabova, Sergey Khasabov, Justin Paz, Catherine Harding-Rose, Donald A. Simone, and Virginia S. Seybold. (2012). Cannabinoid Type-1 Receptor Reduces Pain and Neurotoxicity Produced by Chemotherapy. The Journal of Neuroscience, 32(20): 7091-7101; doi: 10.1523/​JNEUROSCI.0403-12.2012
39. Robert P. Watson, Elliot Lilley, Moh Panesar, Gurdip Bhalay, Steven Langridge, Shin-Shay Tian, Conor McClenaghan, Anna Ropenga, Fanning Zeng, Mark S. Nash. (2012). Increased prokineticin 2 expression in gut inflammation: role in visceral pain and intestinal ion transport. Neurogastroenterology & Motility, Volume 24, Issue 1, pages 65–e12. doi: 10.1111/j.1365-2982.2011.01804.x
40. Sarah E. Canetta, Edlira Luca, Elyse Pertot, Lorna W. Role, David A. Talmage. (2011). Type III Nrg1 Back Signaling Enhances Functional TRPV1 along Sensory Axons Contributing to Basal and Inflammatory Thermal Pain Sensation. PLoS ONE, 6(9): e25108. doi: 10.1371/journal.pone.0025108
41. Mahendra Bishnoi, Christine A Bosgraaf, Mruvil Abooj, Linlin Zhong, Louis S Premkumar. (2011). Streptozotocin-Induced Early Thermal Hyperalgesia is independent of Glycemic State of Rats: Role of Transient Receptor Potential Vanilloid 1(TRPV1) and inflammatory mediators.   Molecular Pain, 7:52. doi: 10.1186/1744-8069-7-52
42. Mariusz Mucha, Lezanne Ooi, John E. Linley, Pawel Mordaka, Carine Dalle, Brian Robertson, Nikita Gamper, and Ian C. Wood. (2010). Transcriptional Control of KCNQ Channel Genes and the Regulation of Neuronal Excitability.J. Neurosci., 30: 13235 - 13245. doi: 10.1523/JNEUROSCI.1981-10.2010
43. James P. Lund,Somayeh Sadeghi,Tuija Athanassiadis, Nadia Caram Salas, François Auclair, Benoît Thivierge, Isabel Arsenault, Pierre Rompré, Karl-Gunnar Westberg, and Arlette Kolta. (2010). Assessment of the Potential Role of Muscle Spindle Mechanoreceptor Afferents in Chronic Muscle Pain in the Rat Masseter Muscle. PLoS One, 5(6): e11131. doi: 10.1371/journal.pone.0011131
44. E. Matthew Hoffman, Ruben Schechter, and Kenneth E. Miller. (2010). Fixative Composition Alters Distributions of Immunoreactivity for Glutaminase and Two Markers of Nociceptive Neurons, Nav1.8 and TRPV1, in the Rat Dorsal Root Ganglion. J. Histochem. Cytochem., 58: 329 - 344.
45. Hao Sun, De-Pei Li, Shao-Rui Chen, Walter N. Hittelman and Hui-Lin Pan. (2009). Sensing of Blood Pressure Increase by Transient Receptor Potential Vanilloid 1 Receptors on Baroreceptors. The Journal of Pharmacology and Experimental Therapeutics, doi: 10.1124/jpet.109.160473
46. Noritaka Imamachi, Goon Ho Park, Hyosang Lee, David J. Anderson, Melvin I. Simon, Allan I. Basbaum, and Sang-Kyou Han. (2009). TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms. PNAS, 106: 11330 - 11335. doi: 10.1073/pnas.0905605106
47. Djalil Baiou, Peter Santha, Antonio Avelino, Ana Charrua, Timea Bacskai, Klara Matesz, Francisco Cruz, Istvan Nagy. (2007). Neurochemical characterization of insulin receptor-expressing primary sensory neurons in wild-type and vanilloid type 1 transient receptor potential receptor knockout mice. J. Comp. Neurol., 503 (2), 334-347.
48. T. NAKAGAWA, K. WAKAMATSU, N. ZHANG,  S. MAEDA, M. MINAMI, M. SATOH AND S. KANEKO. (2007). INTRATHECAL ADMINISTRATION OF ATP PRODUCES LONG-LASTING ALLODYNIA IN RATS: DIFFERENTIAL MECHANISMS IN THE PHASE OF THE INDUCTION AND MAINTENANCE. Neuroscience, 147. 445–455. doi: 10.1016/j.neuroscience.2007.03.045
49. Amol M. Patwardhan, Nathaniel A. Jeske, Theodore J. Price, Nikita Gamper, Armen N. Akopian, and Kenneth M. Hargreaves. (2006). The cannabinoid WIN 55,212-2 inhibits transient receptor potential vanilloid 1 (TRPV1) and evokes peripheral antihyperalgesia via calcineurin. PNAS,  103: 11393-11398. doi: 10.1073/pnas.0603861103
50. Ahluwalia J, Rang H, and Nagy I. (2002). The putative role of vanilloid receptor-like protein-1 in mediating high threshold noxious heat-sensitivity in rat cultured primary sensory neurons. Eur J Neurosci, 16:1483-1489. doi: 10.1046/j.1460-9568.2002.02231.x
51. Hong S, and Wiley JW. (2005). Early painful diabetic neuropathy is associated with differential changes in the expression and function of vanilloid receptor 1. J Biol Chem, 280(1):618-27. doi: 10.1074/jbc.M408500200
52. Hwang SJ, Burette A, and Valtschanoff JG. (2003). VR1-positive primary afferents contact NK1-positive spinoparabrachial neurons. J Comp Neurol, 460:255-265. doi: 10.1002/cne.10647
53. Liu M, Liu MC, Magoulas C, Priestly JV, Willmott NJ. (2003). Versatile Regulation of Cytosolic Ca2+ by Vanilloid Receptor I in Rat Dorsal Root Ganglion Neurons. J Biol Chem, 278(7): 5462-5472. doi: 10.1074/jbc.M209111200
54. Price T, Louria M, Candelario-Soto D, Dussor G, Jeske N, Patwardhan A, Diogenes A, Trott A, Hargreaves K and Flores C. (2005). Treatment of trigeminal ganglion neurons in vitro with NGF, GDNF or BDNF: effects on neuronal survival, neurochemical properties and TRPV1-mediated neuropeptide secretion. BMC Neurosci, 6:4. doi: 10.1186/1471-2202-6-4
55. Wadachi R and Hargreaves KM. (2006). Trigeminal Nociceptors Express TLR-4 and CD14: a Mechanism for Pain due to Infection. J Dent Res, 85(1):49-53.

 

1. Masatoshi Yoshikubo, Kimihito Tashima, Masaki Raimura, Yuto Watanabe, Yukiko Noma, and Syunji Horie. (2022). Daikenchuto, a Traditional Kampo Medicine, Facilitates Mucosal Hyperemic Responses through Activation of TRPA1- and TRPV1-Expressing Sensory Nerves in Rat Stomach. Planta Medica International Open 2022; 9(01):72-79. doi: 10.1055/a-1712-8391
2. Yong Chen, Zi-Long Wang, Michele Yeo, Qiao-Juan Zhang, Ana E. Lopez Romero, Hui-Ping Ding, Xin Zhang, Qian Zeng, Sara L. Morales-Lazaro, Carlene Moore, Ying-Ai Jin, Huang-He Yang, Johannes Morstein, Andrey Bortsov, Marcin Krawczyk, Frank Lammert, Manal Abdelmalek, Anna Mae Diehl, Piotr Milkiewicz, Andreas E. Kremer, Jennifer Y. Zhang, Andrea Nackley, Tony E. Reeves, Mei Chuan Ko, Ru-Rong Ji, Tamara Rosenbaum, and Wolfgang Liedtke. (2021). Epithelia-Sensory Neuron Crosstalk Underlies Cholestatic Itch Induced by Lysophosphatidylcholine. Gastroenterology. doi: 10.1053/j.gastro.2021.03.049
3. Xiaofeng Bai, Xuedi Zhang, Chun Wang, Yao Liu, Xuemei Liu, Yu Fan, and Xia Zhang. (2021). Stem Cells from Human Exfoliated Deciduous Teeth Attenuate Trigeminal Neuralgia in Rats. Stem Cells International. doi: 10.1155/2021/8819884
4. Keiichiro Atsumia, Takehiro Yajima, Daisuke Tachiya, Souichi Kokubun, Noriaki Shoji, Takashi Sasano, Hiroyuki Ichikawa, and Tadasu Sato. (2020). Sensory Neurons in the Human Jugular Ganglion. Tissue and Cell, 64:101344. doi: 10.1016/j.tice.2020.101344
5. Mi-sun Kang  and Kyung-Yae Hyun (2020). Antinociceptive and Anti-Inflammatory Effects of Nypa fruticans Wurmb by Suppressing TRPV1 in the Sciatic Neuropathies. Nutrients 2020, 12(1), 135; https://doi.org/10.3390/nu12010135

6. Mohammad Sarif Mohiuddin, Tatsuhito Himeno, Rieko Inoue, Emiri Miura-Yura, Yuichiro Yamada, Hiromi Nakai-Shimoda, Saeko Asano, Makoto Kato, Mikio Motegi, Masaki Kondo, Yusuke Seino, Shin Tsunekawa, Yoshiro Kato, Atsushi Suzuki, Keiko Naruse, Koichi Kato, Jiro Nakamura, and Hideki Kamiya. (2019). Glucagon-Like Peptide-1 Receptor Agonist Protects Dorsal Root Ganglion Neurons against Oxidative Insult. Journal of Diabetes Research Volume 2019, Article ID 9426014, 10 pages https://doi.org/10.1155/2019/9426014

7. Danyou Hu, Changming Wang, Fengxian Li, Shulan Su, Niuniu Yang, Yan Yang, Chan Zhu, Hao Shi, Lei Yu, Xiao Geng, Leying Gu, Xiaolin Yuan, Zhongli Wang, Guang Yu, and Zongxiang Tang. (2017). A Combined Water Extract of Frankincense and Myrrh Alleviates Neuropathic Pain in Mice via Modulation of TRPV1. Neural Plasticity, Volume 2017, Article ID 3710821, 11 pages. doi: 10.1155/2017/3710821
8. Hee Kyung Cho, M.D., Ph.D., So-Yeon Kim, Ph.D., Mi Jung Choi, Seung Ok Baek, M.D., Sang Gyu Kwak, Ph.D., and Sang Ho Ahn, M.D., Ph.D. (2016). The Effect of GCSB-5 a New Herbal Medicine on Changes in Pain Behavior and Neuroglial Activation in a Rat Model of Lumbar Disc Herniation. J Korean Neurosurg Soc, 59(2): 98-105. doi: 10.3340/jkns.2016.59.2.98